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The adrenal gland is a common site of a large spectrum of abnormalities like primary tumors, hemorrhage, metastases, and enlargement of the gland from external hormonal stimulation. Most of these lesions represent nonfunctioning adrenal adenomas and thus warrant a conservative management. Multi-detector computed tomography (CT) and magnetic resonance (MR) imaging are still considered highly specific and complementary techniques for the detection and characterization of adrenal abnormalities. Radiologist can establish a definitive diagnosis for most adrenal masses (i.e., carcinoma, hemorrhage) based on imaging alone. Imaging therefore can differentiate malignant lesions from those benign and avoid unnecessary aggressive management of benign lesions. The article gives an overview of the adrenal lesions and their imaging characteristics seen on CT and MR imaging.
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http://dx.doi.org/10.4103/2156-7514.124088 | DOI Listing |
Minerva Endocrinol (Torino)
September 2025
Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden -
Adrenal cysts are rare lesions that are increasingly discovered incidentally during radiological examinations conducted without suspicion of adrenal disease. Typically benign, hormonally nonfunctional, and asymptomatic, these lesions may occasionally manifest mass effect symptoms such as pain or abdominal discomfort, particularly in large cysts. Management approaches vary from no follow-up to hormonal investigation, imaging follow-up, or adrenalectomy, especially if the cyst is growing or exhibits an atypical appearance.
View Article and Find Full Text PDFCureus
August 2025
Gynaecology, Guy's and St Thomas' NHS Foundation Trust, London, GBR.
Ovarian fibromatosis (OF) is a rare, benign condition that often mimics malignancy, leading to unnecessary oophorectomies. We report the case of a 12-year-old girl presenting with acute right lower abdominal pain and vomiting, with a history of intermittent abdominal pain since age seven. Imaging revealed an enlarged, avascular right adnexa with a solid lesion.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
September 2025
Department of Infectious Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Paragangliomas (PGLs) are rare neuroendocrine tumors originating from the extra-adrenal autonomic paraganglia with a strong genetic background. pathogenic variants are associated with the highest rate of malignancy in PGLs. Most head and neck paragangliomas (HNPGs) are asymptomatic and benign, and multiple metastases are rare.
View Article and Find Full Text PDFJ Wildl Dis
September 2025
Division of Wildlife Conservation, Alaska Dept of Fish and Game, 1300 College Road, Fairbanks, Alaska 99701, USA.
This report describes highly pathogenic avian influenza virus (HPAI) H5N1 infections in carnivores in Alaska, US between 2022 and 2024, including a black bear (Ursus americanus), a brown bear (Ursus arctos), and the first known report of HPAI in an ermine (Mustela ermina). The two bears were cubs, and the ermine was a young adult. The black bear and ermine were euthanized after demonstrating neurologic signs, including circling, blindness, ataxia, or seizures.
View Article and Find Full Text PDFEndocrine
September 2025
Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.