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http://dx.doi.org/10.1097/MPG.0000000000000339 | DOI Listing |
Am Surg
September 2025
Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.
BackgroundLaparoscopic colectomy is standard for uncomplicated diverticulitis (UD) but has higher conversion and morbidity rates in complicated diverticulitis (CD). Robotic colectomy (RC) is increasingly used for both UD and CD. This study compared outcomes of RC for CD and UD and evaluated factors contributing to adverse outcomes.
View Article and Find Full Text PDFElectrolyte depletion syndrome (EDS), also known as McKittrick-Wheelock syndrome, is a rare but life-threatening condition caused by secretory diarrhea from colorectal villous tumors, often accompanied by severe electrolyte imbalances and renal dysfunction. Large, circumferential tumors have traditionally been managed with surgical resection, frequently requiring stoma formation. Recently, endoscopic submucosal dissection (ESD) has emerged as a minimally invasive alternative, although its feasibility for large rectal tumors remains limited.
View Article and Find Full Text PDFSurg Endosc
August 2025
Department of Surgery, Trinity Health Ann Arbor, Ann Arbor, MI, USA.
Background: The specimen extraction incision is the largest during minimally invasive colectomy and conceivably the most painful. We recently adopted natural orifice extraction through the rectum or vagina, leaving only port site incisions for abdominal wall pain. Previous studies demonstrating natural orifice extraction advantages are inconclusive.
View Article and Find Full Text PDFThe treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors. Our case outlines a patient with refractory UC who failed mesalamine, adalimumab, tofacitinib, and vedolizumab.
View Article and Find Full Text PDFJPGN Rep
August 2025
Sheffield Children's Hospital, NHS Foundation Trust Sheffield UK.
Paediatric-onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti-tumour necrosis factor-alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options. Emerging evidence from the adult literature suggests that upadacitinib is effective and safe; however, paediatric data are scarce.
View Article and Find Full Text PDF