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The purpose of the study is to present and discuss a workflow regarding computer-assisted surgical planning for bimaxillary surgery and intermediate splint fabrication. This study describes a protocol starting from wax bite registration to fabrication of the necessary intermediate splint. The procedure is a proof of concept to replace not only the model surgery but also facebow registration and transfer from facebow to articulator. Three different modalities were utilized to obtain this goal: cone beam computed tomography (CBCT), optical dental scanning, and 3-dimensional printing. A universal registration block was designed to register the optical scan of the wax bite to the CBCT data set. Integration of the wax bite avoided problems related to artifacts caused by dental fillings in the occlusal plane of the CBCT scan. Fifteen patients underwent bimaxillary orthognathic surgery. The printed intermediate splint was used during the operation for each patient. A postoperative CBCT scan was taken and registered to the preoperative CBCT scan. The difference between the planned and the actual bony surgical movement at the edge of the upper central incisor was 0.50 ± 0.22 mm in sagittal, 0.57 ± 0.35 mm in vertical, and 0.38 ± 0.35 mm in horizontal direction (midlines). There was no significant difference between the planned and the actual surgical movement in 3 dimensions: sagittal (P = 0.10), vertical (P = 0.69), and horizontal (P = 0.83). In conclusion, under clinical circumstances, the accuracy of the designed intermediate splint satisfied the requirements for bimaxillary surgery.
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http://dx.doi.org/10.1097/SCS.0b013e31829a80d9 | DOI Listing |
BMC Musculoskelet Disord
August 2025
Department of Orthopedics and Traumatology, BHT Clinic Istanbul Tema Hospital, Istanbul, Turkey.
Background: This prospective comparative study aimed to evaluate the efficacy of kinesio-taping (KT), buddy taping (BT), and conventional splinting in managing finger joint sprains and fractures across pediatric and adult populations, with a focus on functional recovery and patient-centered outcomes.
Materials And Methods: A total of 175 patients were randomized into three treatment arms: KT (Group 1, n = 62), BT (Group 2, n = 52), and splinting (Group 3, n = 61). Participants were stratified into pediatric (5-18 years) and adult (18-60 years) subgroups.
Commun Chem
August 2025
Department of Chemistry, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, Japan.
Chemical ligation of oligonucleotides enables assembly of long DNA constructs essential for genome engineering, DNA nanotechnology, and molecular diagnostics, but current methods often require external activators and suffer from reactive intermediate instability. Here we show a reagent-free DNA autoligation strategy based on intramolecular cross-activation between 3'-phosphorothioate (PS) and 5'-dinitrobenzenesulfonamide (DNBSA) termini on a splint DNA, yielding a P3' → N5' phosphoramidate linkage under near-physiological conditions. Ligation proceeds with over 80% yield at 37 °C and pH 8 without external reagents.
View Article and Find Full Text PDFOrthod Fr
July 2025
Institut aquitain de chirurgie du visage, 21 rue François-Lévêque, 33000 Bordeaux, France
Introduction: The integration of digital tools in surgical planning has transformed the collaboration between orthodontists and maxillofacial surgeons, enabling optimized communication between practitioners as well as rapid and nearly unlimited rehearsal and adjustments.
Materials And Methods: A virtual surgical planning protocol based on the "occlusal block" concept is described, structured into two complementary phases. The first phase, led by the orthodontist, involves defining the target occlusion using digital models.
Oral Surg Oral Med Oral Pathol Oral Radiol
April 2025
Department of Orthodontics, TMJ-Orthodontic-Orthognathic Diagnosis and Treatment Center, School and Hospital of Stomatology, China Medical University, Shenyang, China. Electronic address:
Objective: This study aimed to evaluate three-dimensional (3D) condylar and skeletal changes in female adolescents with idiopathic condylar resorption (ICR) following stabilization splint (SS) therapy.
Study Design: This retrospective study included 32 female adolescents (64 condyles) with ICR (mean age 14.3 ± 2.
Int J Oral Maxillofac Surg
April 2025
Department of Oral and Maxillofacial Surgery, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
The surgical outcome of planned Le Fort I osteotomy (LFI) is important for successful orthognathic surgery. The aim of this study was to evaluate the accuracy of LFI using a CAD/CAM intermediate splint by performing a three-dimensional (3D) comparison of the planned and postoperative maxillary positions. This retrospective study evaluated 31 patients who underwent LFI with a CAD/CAM intermediate splint.
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