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Background. The explosive growth of Hispanics in the US makes this population a significant and untapped source for blood donation. Methods. A cross-sectional study was performed to evaluate blood donation behaviors and demographics of foreign-born and US-born Hispanic donors between 2006 and 2009 in metropolitan Atlanta, GA, USA. Bivariate analyses and multivariate logistic regression were used to assess factors associated with foreign-born donors. Results. 5,119 foreign-born and 11,841 US-born Hispanics donated blood. Foreign-born Hispanic donors were more likely than US-born donors to be blood group O (57.6% versus 52.0%; P < .001) and more frequent donors (2.2 versus 2.0; P < .001). Cuban-born donors had the highest rates of return donation (63.2%). In contrast, Mexicans, the most prevalent subpopulation among foreign-born Hispanic donors (31.8%), had the lowest rates of return donation (42.0%). Conclusions. The heterogeneity found among Hispanic donors in this study is valuable for the design of recruitment strategies to increase blood donations.
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http://dx.doi.org/10.1155/2012/820514 | DOI Listing |
Blood Cell Ther
August 2025
Leukemia/Bone Marrow Transplant Program of British Columbia, Vancouver, Canada.
Introduction: The impact of race on outcomes of allogeneic hematopoietic cell transplants (HCT) has long been a field of research. The Center for International Blood and Marrow Transplant Research (CIBMTR) studies have shown worse survival for Black and Hispanic patients within the first year after HCT, but rates evened out for one-year survivors. From our personal experience, we hypothesize that the outcomes of South Asians (age ≥ 45 years) receiving myeloablative conditioning (MAC) are also worse compared to other races.
View Article and Find Full Text PDFNat Genet
September 2025
Department of Neurology, School of Medicine, University of California, Davis, Sacramento, CA, USA.
To understand shared and ancestry-specific genetic control of brain protein expression and its ramifications for disease, we mapped protein quantitative trait loci (pQTLs) in 1,362 brain proteomes from African American, Hispanic/Latin American and non-Hispanic white donors. Among the pQTLs that multiancestry fine-mapping MESuSiE confidently assigned as putative causal pQTLs in a specific population, most were shared across the three studied populations and are referred to as multiancestry causal pQTLs. These multiancestry causal pQTLs were enriched for exonic and promoter regions.
View Article and Find Full Text PDFLiver Transpl
August 2025
Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Bone Marrow Transplant
August 2025
University of Virginia Comprehensive Cancer Center, Charlottesville, VA, USA.
Randomized clinical trials are expensive and not always practice changing. The Blood and Marrow Transplant Clinical Trials Network (CTN) 1101 trial (2012-2018) showed a lower two-year overall survival after umbilical cord blood (UCB) compared to haploidentical graft (haplo) transplants. To quantify the change in graft utilization after the trial's publication, a cohort of 11,190 U.
View Article and Find Full Text PDFKidney Int Rep
August 2025
Regenstrief Institute, Indianapolis, Indiana, USA.
Introduction: Although non-Hispanic Black (Black) and non-Hispanic White (White) racial disparities in access to transplantation have decreased over the past 2 decades, it remains unclear whether trends are consistent across all ages and transplant steps.
Methods: We identified 1,091,206 White or Black adults initiating dialysis (cohort 1) and 226,703 adults waitlisted (cohort 2) in the United States Renal Data System (USRDS) from 2005 to 2019, followed through 2021. Study outcomes were as follows: (i) waitlisting (among patients on dialysis), (ii) living donor kidney transplant (LDKT) (among patients on dialysis), and (iii) deceased donor kidney transplant (DDKT) (among waitlisted adults).