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Article Abstract
Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1-4 showed moderate inhibitory activity against the α-glucosidase (with IC₅₀ values ranging from 1,812 to 2,027 μM).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270363 | PMC |
| http://dx.doi.org/10.3390/molecules18078518 | DOI Listing |
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Two new chiratane-type triterpenoids from Swertia kouitchensis.
Molecules
July 2013
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1-4 showed moderate inhibitory activity against the α-glucosidase (with IC₅₀ values ranging from 1,812 to 2,027 μM).
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