Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
3-(4-Chlorophenyl)-4-substituted pyrazole derivatives were synthesised and tested for their in vitro antifungal activity. Some compounds showed very good antifungal activity against four pathogenic strains of fungi. The same compounds exhibited an interesting activity against the tested strain of Mycobacterium tuberculosis H37Rv. The results suggest that 1,3,4-oxadiazoles and 5-pyrazolinones bearing a core pyrazole scaffold may be promising antifungal and antitubercular agents.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3ob27290g | DOI Listing |
Publication Analysis
Top Keywords
3-4-chlorophenyl-4-substituted pyrazole
8
pyrazole derivatives
8
antifungal activity
8
synthesis biological
4
biological evaluation
4
evaluation 3-4-chlorophenyl-4-substituted
4
derivatives 3-4-chlorophenyl-4-substituted
4
derivatives synthesised
4
synthesised tested
4
tested vitro
4