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We evaluated whether differences in treatment effectiveness or preference between languages emerged across Spanish and English during functional communication training (FCT) for young children with developmental disabilities exposed to Spanish and English in the home environment. Participants were 2 young children with developmental disabilities who displayed destructive behavior maintained by social contingencies and whose families spoke Spanish and English at home. All procedures were conducted in the participants' homes by their mothers with coaching from the investigator. The effectiveness of FCT was evaluated within a reversal design across baseline, FCT, and extinction conditions. A multielement design across language type (Spanish and English) was embedded within the reversal design during the extinction and FCT conditions to evaluate differences in treatment effectiveness across type of language. Finally, during all FCT sessions, a concurrent schedules design was used to evaluate participant preference for type of language. Results suggested that FCT was effective in reducing destructive behavior, increasing manding, and/or increasing task completion for these 2 participants across Spanish and English treatment conditions. Preference for the type of language did not emerge for either participant during FCT. Results are discussed in terms of the merits of systematically evaluating language variables when working with culturally and linguistically diverse families and children.
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http://dx.doi.org/10.1007/s10864-011-9131-z | DOI Listing |
Stroke
September 2025
Department of Neurology, Yale School of Medicine, New Haven, CT (L.H.S.).
Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, G1 1XL, UK.
We present a study of the ability of our recently reported well-defined crown ether-coordinated alkali metal phosphides 1 to catalyze hydrophosphination (HP) of alkynes and alkenes. In a comparative study including reaction monitoring by H NMR spectroscopy, we show that the activity of caesium compound 1 greatly exceeds that of its lighter congeners, enabling us to solve some reported challenges of catalytic hydrophosphination. Through the rarely used application of dialkyl phosphines, we were able to produce trialkyl phosphines from HP of styrene derivatives and activated as well as non-activated alkynes by catalytic HP with BuPH and BuPH.
View Article and Find Full Text PDFFASEB J
September 2025
School of Biodiversity, One Health and Veterinary Medicine, Graham Kerr Building, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Most animals experience abrupt developmental transitions involving major tissue remodeling, but the links with metabolic changes remain poorly understood. We examined ontogenetic changes in mitochondrial volume, oxidative capacity, oxygen consumption capacity, and anaerobic capacity across four organs (gut, liver, heart, and hindlimb muscle) in Xenopus laevis from metamorphosis to adulthood. These organs differ in the extent of developmental transformation.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Institution Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA Nanoscience), Madrid, 28049, Spain.
Achieving magnetic ordering in low-dimensional materials remains a key objective in the field of magnetism. Herein, coordination chemistry emerges as a powerful discipline to promote the stabilization of magnetism at the nanoscale. We present a thorough study of exemplary two-dimensional metal-organic nanoarchitectures synthesized on a Au(111) substrate, which are rationalized by using surface-science techniques and theoretical calculations.
View Article and Find Full Text PDFAdv Mater
September 2025
Instituto de Ciencia Molecular (ICMol), Universidad de Valencia, Calle Catedrático José Beltrán 2, Paterna, 46980, Spain.
Formamidinium lead iodide perovskite compositions have a low open circuit voltage deficit and thus a higher power conversion efficiency (PCE) potential. However, their low bandgap makes it difficult to achieve a semitransparent perovskite solar cell (ST-PSC) with a high average visible transmittance (AVT) and thus, a high light utilization efficiency (LUE). Attaining a high AVT in such low bandgap perovskite‑based semitransparent solar cells requires the perovskite layer to be very thin (thickness < ≈100 nm) and the rear electrode to be made of a transparent conductive oxide.
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