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http://dx.doi.org/10.1073/pnas.1304867110 | DOI Listing |
Cureus
August 2025
Faculty of Medicine, University of Costa Rica, San Jose, CRI.
This systematic review examines the potential association between semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, and the development of non-arteritic anterior ischemic optic neuropathy (NAION). Nine studies were included, consisting of retrospective cohort analyses, case series, and pharmacovigilance reports. Findings across the literature were inconsistent, with some studies reporting an increased risk while others found no significant association.
View Article and Find Full Text PDFInflamm Bowel Dis
September 2025
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Background: Ulcerative colitis (UC) is a gastrointestinal inflammatory condition with an unclear etiology. Recent findings suggest that metabolites play a pivotal role in promoting intestinal health. We have previously observed a significant enrichment in colonic branched-chain amino acids (BCAAs) in resistant mice to colitis suggesting the potential role of these metabolites in UC development.
View Article and Find Full Text PDFEpilepsy Behav
September 2025
City St George's, University of London, London, UK; King's College London, UK.
Background: People with epilepsy are at greater risk of experiencing anxiety, depression, and low self-compassion. One psychological intervention with a growing evidence base in people with long-term physical health conditions (LTCs) is compassion-focused therapy (CFT), yet research remains limited in epilepsy populations.
Aims: This study aimed to evaluate the effectiveness of an online CFT-based group intervention in decreasing anxiety and depression and increasing self-compassion among adults with epilepsy.
Int J Eat Disord
September 2025
Department of General Psychology, University of Padova, Padova, Italy.
Smartphone applications (apps) represent promising tools to overcome common barriers to treatment in individuals within the Eating Disorders (EDs) spectrum, thanks to their constant availability and cost-effectiveness. In this context, Cruz et al. (2025) conducted the first meta-analysis of randomized controlled trials (RCTs) evaluating the efficacy of app-based interventions for EDs.
View Article and Find Full Text PDF