98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.seizure.2013.04.011 | DOI Listing |
J Clin Med
June 2025
Neuroradiology Department, 'Magna Graecia' University, 88100 Catanzaro, Italy.
The radiological finding of Dark White Matter (DWM)-characteristic diffuse subcortical white matter hypointensity on T2/FLAIR sequences-is underrecognized, but has important clinical implications. Recent systematic evidence shows that over 60% of previously published cases showed seizures in association with DWM findings-it is also particularly predictive of the underlying etiology, particularly non-ketotic hyperglycemic hyperosmolar state (NKH). Based on our previous work, we reinterpret the data, focusing only on patients with seizures and DWM, to summarize the most essential and distinguishing features of these patients.
View Article and Find Full Text PDFBrain
June 2025
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.
How do brain networks limit seizure activity? In the Interictal Suppression Hypothesis, we recently postulated that high inward connectivity to seizure onset zones (SOZs) from non-involved zones (NIZs) is a sign of broader network suppression. If broad networks appear to be responsible for interictal SOZ suppression, what changes during seizure initiation, spread, and termination? For patients with drug-resistant epilepsy, intracranial monitoring offers a view into the electrographic networks which organize around and in response to the SOZ. In this manuscript, we investigate network dynamics in the peri-ictal periods to assess possible mechanisms of seizure suppression and the consequences of this suppression being overwhelmed.
View Article and Find Full Text PDFEpileptic Disord
May 2025
Department of Neuropediatrics, University Children's Hospital, University of Zurich, Zurich, Switzerland.
The "chapeau de gendarme" sign, also known as "ictal pouting," is a distinctive facial expression observed in focal epilepsy, characterized by a turned-down mouth with symmetrical lip and chin contraction. This systematic review investigates its clinical relevance, anatomical origins, and diagnostic value, particularly in presurgical evaluation. The sign is most commonly associated with mesial frontal epilepsy, particularly involving the anterior cingulate cortex (ACC), though moderate evidence links it to a broader network including insulo-opercular and temporo-parietal regions.
View Article and Find Full Text PDFBrain Inj
August 2025
Department of Pediatrics, Taipei Veterans General Hospital, Taipei City, Taiwan.
Objective: Hypertensive encephalopathy may complicate the course of pediatric nephrotic syndrome, and the resulting brain injury is not always reversible. Subclinical electroencephalographic activities may play a role in this context, as demonstrated by the case vignette.
Method: We report on a girl with IgA nephropathy and secondary hypertension, leading to posterior reversible encephalopathy syndrome (PRES).
Eur J Pediatr
March 2025
Paediatric Neurology and Neurophysiology Unit, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy.
Unlabelled: Subpial hemorrhage (SPH) is a rare subtype of intracranial hemorrhage, predominantly affecting term neonates and often associated with cortical-subcortical infarction. We described the epidemiology of SPH by analyzing cases referred to our hospital and concurrently conducting a systematic review of the cases reported in the literature. We also illustrated factors associated with adverse outcomes.
View Article and Find Full Text PDF