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Providing a satisfactory, functional prosthesis following lower-limb amputation is a primary goal of rehabilitation. The objectives of this study were to describe the rate of successful prosthetic fitting over a 12 mo period; describe prosthetic use after amputation; and determine factors associated with greater prosthetic fitting, function, and satisfaction. The study design was a multicenter prospective cohort study of individuals undergoing their first major lower-limb amputation because of vascular disease and/or diabetes. At 4 mo, unsuccessful prosthetic fitting was significantly associated with depression, prior arterial reconstruction, diabetes, and pain in the residual limb. At 12 mo, 92% of all subjects were fit with a prosthetic limb and individuals with transfemoral amputation were significantly less likely to have a prosthesis fit. Age older than 55 yr, diagnosis of a major depressive episode, and history of renal dialysis were associated with fewer hours of prosthetic walking. Subjects who were older, had experienced a major depressive episode, and/or were diagnosed with chronic obstructive pulmonary disease had greater functional restriction. Thus, while most individuals achieve successful prosthetic fitting by 1 yr following a first major nontraumatic lower-limb amputation, a number of medical variables and psychosocial factors are associated with prosthetic fitting, utilization, and function.
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http://dx.doi.org/10.1682/jrrd.2012.01.0001 | DOI Listing |
J Neurosurg
September 2025
1Division of Hand and Microvascular Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Objective: The role of amputation and myoelectric prosthetic fitting for hand function in traumatic pan-brachial plexus injury (pBPI) continues to evolve. This study evaluated the function and activity performance of patients with traumatic pBPI who underwent amputation and prosthetic fitting with a myoelectric prosthesis (MEP) for hand function.
Methods: A retrospective analysis of adult patients who underwent elective amputation after sustaining a pBPI followed by MEP for hand function was performed.
Can Prosthet Orthot J
February 2025
Department of Biomedical Engineering, Faculty of Engineering, University of Strathclyde, Glasgow, Scotland.
Background: Poor post-amputation healing delays prosthetic fitting, adversely affecting mortality, quality of life, and cardiovascular health. Current residual limb assessments are subjective and lack standardized guidelines, emphasizing the need for objective biomarkers to improve healing and prosthesis readiness assessments.
Objectives: This review aimed to identify predictive, diagnostic, and indicative chemical biomarkers of healing of the tissues and structures found in the residual limbs of adults with amputation.
Gait Posture
August 2025
Clinical Research and Services, Research Biomechanics, Ottobock SE & Co. KGaA, Göttingen, Germany; HAWK University of Applied Sciences and Arts, Göttingen, Germany. Electronic address:
Background: Prosthetic fittings for persons with a transfemoral amputation should provide adequate ground clearance (GC) during prosthetic side swing to minimize the risk of stumbling or falling. Insufficient ground clearance often leads to compensatory movements that consequently influence gait biomechanics negatively.
Research Question: How do different prosthetic components and alignment of a transfemoral prosthesis affect prosthetic side GC and compensatory strategies during level walking?
Methods: Eight persons with transfemoral amputation were enrolled.
Phys Ther
August 2025
New York Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, United States.
Importance: Lower extremity amputation (LEA) is a worldwide public health problem leading to large disability burdens and health care costs. After LEA, prostheses improve functional mobility and quality-of-life. However, health care costs are high and prosthetic provision worldwide unknown.
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August 2025
Department of Prosthodontics and Crown and Bridge, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi mehge, Wardha, Maharashtra, India.
Background: Edentulism, the absence or total loss of all-natural teeth, is a common condition. Severe resorption of the residual alveolar ridge is one of the most common problems among edentulous patients, and it can still happen even with careful prosthetic therapy. Thus, the stability and retention of fully edentulous patients utilizing complete denture prostheses is one of the most significant challenges in dentistry today.
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