98%
921
2 minutes
20
Studies concerning persons living with HIV (PLWH) report that stressful life events (SLEs) contribute to an exacerbation of symptoms and reduced antiretroviral (ARV) adherence and quality of life (QOL). Little is known about whether these findings are site-specific. Our study's aims were to characterize the type and frequency of SLEs for PLWH in Puerto Rico, South Africa, and the United States, and to assess the impact of SLEs by national site, symptoms, and ARV adherence concerns on QOL. The sample consisted of 704 participants. The total number of SLEs correlated significantly with the total number of symptoms, adherence concerns, and QOL (p ≤ .001). Overall, 27.2% of the variance in QOL was explained by the aforementioned variables. Although SLEs were of concern to PLWH, worries about ARV adherence were of even greater concern. Routine assessment of ARV concerns and SLEs can promote ongoing ARV adherence and improved QOL.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681926 | PMC |
http://dx.doi.org/10.1016/j.jana.2012.11.005 | DOI Listing |
Int J STD AIDS
September 2025
Centre for Communicable Diseases Control and Research, Federal Medical Centre, Asaba, Nigeria.
BackgroundMother-to-Child Transmission (MTCT) of HIV continues to be a critical public health issue, particularly in high-prevalence regions. This study examines the rates of MTCT in relation to antenatal booking, parity, antiretroviral (ARV) use, delivery mode, CD4 counts, and infant feeding practices.MethodsA retrospective cross-sectional study was conducted at the Federal Medical Centre, Asaba, Nigeria, involving pregnant women living with HIV attending the Prevention of Mother-to-Child Transmission (PMTCT) program.
View Article and Find Full Text PDFJ Infect Public Health
September 2025
AP-HP, Hospital Bichat - Claude-Bernard, Infectious and Tropical Diseases Department, IAME UMR 1137 INSERM, Université Paris Cité, France; IMEA, Hospital Bichat-Claude Bernard, Paris, France.
Background: Polymedication and comorbidities are frequent in aging people with HIV (PWH) and often associated with elevated incidences of adverse events (AEs) and drug-drug interactions (DDIs). The objective of this study was to evaluate the efficacy, safety and practicality of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF), an antiretroviral (ARV) therapy with limited DDIs, in an elderly virologically-controlled PWH population.
Materials And Methods: This study was prospective, multicentric, single-arm conducted in HIV-1 controlled PWH aged over 65 years who switched from a ritonavir- or cobicistat-boosted containing regimen to B/F/TAF.
PLoS One
September 2025
School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Background: Female sex workers (FSWs) are at an elevated risk of HIV infection with an eight-fold risk of HIV infection. In countries like Zimbabwe, FSWs have an HIV incidence of around 10.2%.
View Article and Find Full Text PDFInt J MCH AIDS
July 2025
Department of Pharmacology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Background And Objective: There is a global effort to eliminate new human immunodeficiency virus (HIV) infections among children. However, mother-to-child transmission (MTCT) of HIV, which accounts for nearly all pediatric infections, remains disproportionately high in Africa, including Ghana. This study aims to determine the prevalence and identify the key predictors of MTCT of HIV among HIV-exposed infants in the Ashanti Region of Ghana.
View Article and Find Full Text PDFFront Public Health
August 2025
Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Globally, there are approximately 1·5 million children (0-14 years old) living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), of which 90% are in sub-Saharan Africa. South Africa has the most extensive pediatric HIV care and treatment program. Statistical data from 2023 demonstrated that 152,984 South African children (<15 years) were living with HIV.
View Article and Find Full Text PDF