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Environmental microbiota as a regulator of children's health: a one health perspective.

Int J Environ Health Res

September 2025

Unidad Interinstitucional de Investigación Clínica y Epidemiológica, Facultad de Medicina, Universidad Autónoma de Yucatán, Mérida, México.

The human microbiota consists of millions of microorganisms, predominantly bacteria, that inhabit the body and form communities. Each human body site has a unique population that is specifically adapted to complement the metabolic functions of the environments in which they are present. These microbial communities begin to form at birth, with their primary establishment occurring during the early years of childhood and persisting in adulthood.

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Protecting Canada's youth from the risks of exposure to gambling advertising.

CMAJ

September 2025

Medical editor, CMAJ (Charlebois), Ottawa, Ont.; London School of Hygiene and Tropical Medicine (Charlebois), London, UK; Department of Pediatrics (Kelly), Faculty of Medicine, University of Ottawa; Department of Psychiatry (Kelly), Children's Hospital of Eastern Ontario; Canadian Society of Addicti

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Background: Health awareness is an important factor in preventive health and healthy lifestyles of children and adolescents with an intellectual disability. The research objective is therefore to explore the perspective of people with intellectual disability regarding their health-related experiences and the meanings they assign to health.

Methods: Using interpretative phenomenological analysis (IPA) as a methodological approach, semi-structured interviews were conducted with 14 students between the ages of 13 and 19.

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Many new biologic treatments and small molecule agents are emerging and being approved for treating atopic dermatitis (AD). Robust evidence, based on large sample sizes from real-world clinical settings, are needed to investigate the use of these new therapies, However, adequate sample sizes of patient data are difficult to obtain within one country alone, requiring international collaboration and data aggregation. To address this need for cooperative research, we investigated the feasibility for an international collaboration of registries to gather data from real-world clinical settings on patients' use of new systemic treatments for AD by creating a federated network between national registries that enables an analysis environment protecting privacy of information and ensuring compliance with General Data Protection Regulation.

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In low- and middle-income countries (LMICs), close cohabitation with animals and limited access to water, sanitation, and hygiene (WASH) infrastructure increase the risk of zoonotic enteric pathogen transmission to young children. This mixed-methods study combined (A) microbiological analysis of 120 animal fecal samples, and (B) go-along, semi-structured interviews with 35 mothers of children under two years across urban, intermediate, and rural communities in Ecuador to investigate: (Q1) What zoonotic enteric pathogens are present in animal feces and at what concentrations? (Q2) How are children exposed to animals and their feces? and (Q3) Which animals may serve as key sources of child? Microbiological analysis revealed high prevalence and concentrations of zoonotic pathogens, most commonly aEPEC (57%), sp. (36%), and STEC (25%), with frequent co-infections (33%) and concentrations (4.

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