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The aim of this study was to examine the effects of an 8-week speed training program on the acceleration ability and maximum speed at 11 years athletes. A total of 30 healthy female athletes volunteered to participate in this study. They were divided randomly into 1 of 2 groups: Experimental group (EG; N = 15) and control group (CG; N = 15). The mean (SD) age was 11.20 +/- 0.32 years, height was 1.44 +/- 0.08 m, and weight was 35.20 +/- 2.02 kg for the experimental group; the mean (SD) age was 11.40 +/- 0.39 years, height was 1.45 +/- 0.05 m, and weight was 36.06 +/- 1.15 kg for the control group. A speed training program was applied to the subjects 3 days a week for 8 weeks. Testing was conducted before and after 8 weeks of training. Acceleration and maximum speed was evaluated for 15-m and 30-m, respectively, involving sprinting 15 m and 30 m as fast as possible from a stationary start position that was ascertained during a 50-m. Electronic timekeeping was conducted by the facility--Brower Timing System--made in Utah, USA., consisting of 4 components. Paired t-tests detected significant differences in pre- and posttests for clearance time of 5 m during 50 m in the experimental and control groups (p < 0.05). Therefore, acceleration phase was significantly reduce at 15 m distance interval for the experimental group and control groups posttraining than pretraining (0-15 m, p < 0.05). Acceleration improvement was 12.6% for the experimental group posttraining, on the other hand, acceleration improvement was 5% for the control groups posttraining. we did not find significant difference between pretest and posttest in 10-15 m, 15-20 m, and 20-25 m for the experimental group (p > 0.05). On the other hand, we did find significant difference between pretest and posttest values of other clearance times of consecutively each 5m during 50 m for the experimental and control groups (p < 0.05). Also, this study observed that athletes reached maximum speed in 30 m. In conclusion, in speed training, it is important to improve as many fast motor units as possible, which are more suitable for fast movements. The gains in sprint performance occurred in the initial acceleration and speed-maintenance phases. The ability to accelerate quickly from a stationary position will provide a competitive advantage for athletes.
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J Intern Med
September 2025
Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University Bochum, Bochum, Germany.
Background: High-density lipoprotein (HDL) function, rather than its concentration, plays a crucial role in the development of coronary artery disease (CAD). Diminished HDL antioxidant properties, indicated by elevated oxidized HDL (nHDL) and diminished paraoxonase-1 (PON-1) activity, may contribute to vascular dysfunction and inflammation. Data on these associations in CAD patients, including acute coronary syndrome (ACS), remain limited.
View Article and Find Full Text PDFJ Cogn Dev
March 2025
Department of Communicative Sciences and Disorders, New York University, 665 Broadway, New York, New York 10012.
This research paper explores the role of speaker, listener and real-time social attention for pronoun comprehension in autistic and nonautistic children in northeast United States. We assessed the pronoun comprehension of 22 autistic children (average age of 62 months, range 46-80 months) and 22 nonautistic children (average age 44 months, range 30-57 months) matched on expressive vocabulary scores. We evaluated first- and second-person possessive pronoun comprehension ("my" and "your") using a game in which two experimenters hid stickers and provided clues to their location by providing a verbal clue (e.
View Article and Find Full Text PDFJ Immunother Precis Oncol
August 2025
The Christie NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom.
Introduction: Patients with advanced solid tumors may be considered for early phase clinical trials investigating the safety, tolerability, and dosing of experimental therapies. Optimizing participant selection is critical to maximize clinical benefit and meet trial endpoints with fewer participants. One in six participants does not meet routine life expectancy requirements (>3 months), highlighting the need for improved prognostication.
View Article and Find Full Text PDFTransl Anim Sci
August 2025
Department of Animal Science - Texas A&M University, College Station, TX 77843, USA.
This experiment evaluated the effects of supplementing yeast culture ( ) on in situ ruminal degradability, rumen fermentation and microbiota responses of heifers consuming a forage-based diet. Twelve ruminally-cannulated Angus-influenced heifers were ranked by body weight ( 180 ± 4 kg) and assigned to 4 groups of 3 heifers each. Groups were enrolled in a replicated 3 × 3 Latin square design containing 3 periods of 21 d and 14-d washout intervals.
View Article and Find Full Text PDFTransl Anim Sci
August 2025
Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA.
During disease, there may be increased local demands for zinc (Zn) and vitamin A to support pathogen response. This study evaluates the effects of intranasal Zn and vitamin A treatments on steers experimentally infected with bovine respiratory disease (BRD) pathogens, bovine respiratory syncytial virus (BRSV) and , hypothesizing that steers treated with Zn and vitamin A (VA) will have improved recovery to BRD challenge. Forty-eight Angus crossbred steers (333 ± 4.
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