Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: To verify the safety and clinical use of non-invasive high-voltage electrical stimulation (HVES) in patients with compressive radiculopathy. To test the feasibility of HVES to survey nerve root function during lumbosacral surgery.
Methods: In 20 patients undergoing lumbosacral surgery for degenerative spinal diseases, compound muscle action potentials (CMAPs) evoked by maximal HVES were bilaterally recorded throughout surgery from L3 to S2 radicular territories. A preliminary study was performed in awake patients to rule out detrimental effects caused by HVES.
Results: Preoperative study confirmed the safety of HVES. Unexpectedly, a transient but significant remission of pain was observed after root stimulation. Intraoperative monitoring (IOM) was accomplished in all patients. HVES never hindered surgical procedures and never caused mechanical damage within the operatory field. In 4 patients acute, highly focal and reversible conduction failure was promptly detected by HVES in radicular territories congruent with the root manipulated at that moment.
Conclusions: HVES is a safe and sensitive tool to monitor nerve root function in lumbosacral surgery.
Significance: The method is based on the assumption that any acute conduction failure occurring during surgery can be immediately and unambiguously detected by HVES if root stimulation is supramaximal and delivered rostral to the surgical level.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.clinph.2012.10.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Endothelin B receptor inhibition rescues aging-dependent neuronal regenerative decline.
Elife
September 2025
Department of Neuroscience, Washington University School of Medicine, St Louis, United States.
Peripheral sensory neurons regenerate their axons after injury to regain function, but this ability declines with age. The mechanisms behind this decline are not fully understood. While excessive production of endothelin 1 (ET-1), a potent vasoconstrictor, is linked to many diseases that increase with age, the role of ET-1 and its receptors in axon regeneration is unknown.
View Article and Find Full Text PDFVolumetric measurement of herniated disc material as a predictor of outcome in periradicular therapy.
Eur Spine J
September 2025
Faculty of Health, Witten/Herdecke University, Witten, Germany.
Purpose: The aim of this study was to analyze the correlation between volume change in disc herniations and pain improvement after CT guided periradicular therapy.
Methods: Between 5/2017 and 9/2023 46 volumetric MRI examinations of 18 patients suffering from lower back pain were compared to a control group, prior to and following periradicular infiltration therapy. The performed procedure included an image guided application of a glucocorticoid, a local anesthetic and a contrast agent close to the affected nerve root.
Significant pain reduction in refractory post-mastectomy pain syndrome with closed-loop spinal cord stimulation: illustrative cases.
J Neurosurg Case Lessons
September 2025
Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Background: Breast cancer is one of the most common malignancies worldwide and is often treated with surgery. Post-mastectomy pain syndrome (PMPS) can have disabling consequences. The incidence of PMPS ranges from 20% to 68%.
View Article and Find Full Text PDFPostoperative Cauda Equina Syndrome Revealing a Delayed-Onset Dural Tear Following Lumbar Spine Surgery: A Case Report.
Cureus
August 2025
Department of Research for Spine and Spinal Surgery, Fukushima Medical University, Fukushima, JPN.
Dural tears are a well-known complication of spinal surgery. While most occur intraoperatively and are promptly identified, some are overlooked or develop postoperatively. Delayed-onset dural tears are relatively rare but can result in significant neurological complications, including cauda equina syndrome (CES).
View Article and Find Full Text PDFImpact on the Intervertebral Foramen After Posterior Cervical Fixation Surgery Using Cervical Pedicle Screws.
Cureus
August 2025
Orthopaedic Surgery, Kobe Rosai Hospital, Kobe, JPN.
Purpose We aimed to compare postoperative changes in intervertebral foraminal areas and the mechanisms of foraminal stenosis following fixation surgery for cervical spondylotic myelopathy (CSM) with local kyphosis and instability, using three-dimensional computed tomography (3DCT). Methods We retrospectively analyzed 55 patients who underwent posterior cervical spinal fixation using pedicle screws. A total of 71 spinal levels (C2/3 to C7/T1) and 144 intervertebral foramina with anchor screws inserted in the upper and lower vertebrae were examined.
View Article and Find Full Text PDF