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Eosinophilic myelitis (EM) or atopic myelitis is a rare disease characterized by a myelitic condition in the spinal cord combined with allergic process. This disease has specific features of elevated serum IgE level, active reaction to mite specific antigen and stepwise progression of mostly the sensory symptoms. Toxocariasis can be related with a form of EM. This report describes two cases of cervical eosinophilic myelitis initially considered as intramedullary tumors. When a differential diagnosis of the intramedullary spinal cord lesion is in doubt, evaluation for eosinophilic myelitis and toxocariasis would be beneficial.
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http://dx.doi.org/10.3340/jkns.2012.52.4.410 | DOI Listing |
Am J Ther
September 2024
Department of Neurology, Jiaxing Second Hospital, Jiaxing, China ; and.
Mult Scler Relat Disord
May 2024
Division of Neurology, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Background: Eosinophils in cerebrospinal fluid (CSF) are an uncommon finding most often associated with parasitic infections, but have also been described in some neuroinflammatory disorders. Eosinophilic infiltration is not thought to be a typical feature of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). We aim to describe the rate of CSF eosinophil positivity in a cohort of pediatric MOGAD patients.
View Article and Find Full Text PDFJ Neuroimmunol
December 2023
Department of Neurology, University of Colorado School of Medicine, Aurora, CO, United States of America. Electronic address:
Cerebrospinal fluid (CSF) eosinophilia is associated with a narrow differential, primarily including parasitic and fungal infections, neoplasm, and chemical meningitis. It has rarely been reported in neuroinflammatory conditions including as a finding of CSF cytology in two autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy cases. Here we describe a case of autoimmune GFAP astrocytopathy with classic clinical and radiographic features as well as presence of eosinophils in the CSF.
View Article and Find Full Text PDFHandb Clin Neurol
August 2023
Department of Neurology, Methodist Neurological Institute, Weill Cornell Medical College, Houston Methodist Hospital, Houston, TX, United States. Electronic address:
Neurohospitalist
January 2023
Department of Medicine, Buriram Hospital, Thailand.