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Aims: To evaluate anterior segment optical coherence tomography (AS-OCT) in the diagnosis and treatment of Descemet's membrane detachment (DMD) with severe corneal edema.
Methods: Nine eyes of 7 consecutive patients with suspected DMD with severe corneal edema due to different causes were imaged with the AS-OCT system. Configuration of Descemet's membrane (DM) was delineated before and after treatment, and quantitative analysis was performed. An appropriate treatment was chosen based on the imaging findings.
Results: DMD was demonstrated as being present in all eyes via AS-OCT. Different statuses of the DM including planar/nonplanar detachment, local/extensive detachment, and rupture was documented using AS-OCT images. Two eyes were treated with conservative therapy, 6 eyes with intracameral air/gas tamponade and 1 eye with penetrating keratoplasty. One of the air tamponade treatments failed and all the other treatments were successful.
Conclusion: AS-OCT is a valuable tool in the diagnosis of DMD both in terms of selecting the appropriate treatment, and monitoring treatment outcomes when corneal edema is present.
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http://dx.doi.org/10.1159/000334946 | DOI Listing |
Cornea
September 2025
Department of Ophthalmology, University of Duesseldorf, Duesseldorf, Germany.
Purpose: To report a case of late dehiscence of an EndoArt implant and its successful management 10 months after initial implantation.
Methods: Case report.
Results: A 73-year-old man with a history of multiple failed Descemet membrane endothelial keratoplasty procedures on the right eye underwent EndoArt implantation for bullous keratopathy.
Cornea
September 2025
Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
Purpose: We report a unique case of recurrent Descemet membrane endothelial keratoplasty (DMEK) failure in a 69-year-old man with a history of pseudophakic bullous keratopathy (PBK) secondary to glaucoma surgeries.
Methods: This is a retrospective case report.
Results: The initial PAUL glaucoma implant was relocated to the sulcus, and the original sclerostomy was plugged with Tutoplast.
Cell Tissue Bank
September 2025
Department of Ophthalmology and Visual Sciences, McGill University, Montreal, Canada.
To summarize the evidence examining the outcomes of Descemet membrane endothelial keratoplasty (DMEK) using eye bank pre-stripped versus surgeon prepared grafts. Systematic review and meta-analysis. This study was conducted following the preferred reporting items for systematic reviews and meta-analyses consensus statement (PROSPERO ID: CRD42023457120).
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September 2025
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India; and.
Purpose: To evaluate the long-term visual, functional outcomes, and complications associated with Deep Anterior Lamellar Keratoplasty (DALK) in pediatric keratoconus (KC).
Methods: A retrospective analysis of children aged ≤18 years who underwent DALK for KC between February 2006 and April 2021. Data on preoperative uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), corneal topography, surgical technique, and complications.
Front Med (Lausanne)
August 2025
Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
To investigate corneal deposits in a patient undergoing long-term chlorpromazine therapy using confocal microscopy with the HRT II Rostock Corneal Module. We reported a 45-year-old woman with a 7-year history of chlorpromazine therapy presented with bilateral photophobia and a 4-year history of gradual-onset blurred vision. Slit-lamp examination revealed yellowish deposits in the corneal endothelium and Descemet's membrane.
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