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Many of the complex systems found in biology are comprised of numerous components, where interactions between individual agents result in the emergence of structures and function, typically in a highly dynamic manner. Often these entities have limited lifetimes but their interactions both with each other and their environment can have profound biological consequences. We will demonstrate how modelling these entities, and their interactions, can lead to a new approach to experimental biology bringing new insights and a deeper understanding of biological systems.
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http://dx.doi.org/10.1039/c1ib00042j | DOI Listing |
J Agric Food Chem
September 2025
Life Sciences and Facility Management, Zurich University of Applied Sciences (ZHAW), Wädenswil 8820, Switzerland.
This study presents the first comprehensive sensory-guided investigation into the odor-active compounds of dried hemp ( L.) flowers. Using gas chromatography-olfactometry (GC-O) in combination with aroma extract dilution analysis (AEDA), 52 odor-active compounds were identified across six cannabidiol-rich cultivars.
View Article and Find Full Text PDFNeurol Neuroimmunol Neuroinflamm
November 2025
Department of Neurology, UC Davis Medical Center, Sacramento, CA.
Objectives: Complement factor I (CFI) deficiency is a rare condition that can present with fulminant relapsing CNS autoinflammation. In this report, we highlight the utility of genetic testing in unexplained CNS autoinflammation.
Methods: This case report describes a young adult with partial CFI deficiency, presenting with acute hemorrhagic leukoencephalitis and longitudinally extensive transverse myelitis.
JMIR Public Health Surveill
September 2025
Center of Indigenous Health Care, Department of Community Health, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.
Background: The COVID-19 pandemic has devastated economies and strained health care systems worldwide. Vaccination is crucial for outbreak control, but disparities persist between and within countries. In Taiwan, certain indigenous regions show lower vaccination rates, prompting comprehensive inquiries.
View Article and Find Full Text PDFChannels (Austin)
December 2025
Biorheology Research Laboratory, Faculty of Health, Griffith University, Gold Coast, Australia.
The hallmarks of mechanosensitive ion channels have been observed for half a century in various cell lines, although their mechanisms and molecular identities remained unknown until recently. Identification of the bona fide mammalian mechanosensory Piezo channels resulted in an explosion of research exploring the translation of mechanical cues into biochemical signals and dynamic cell morphology responses. One of the Piezo isoforms - Piezo1 - is integral in the erythrocyte (red blood cell; RBC) membrane.
View Article and Find Full Text PDFPol Merkur Lekarski
September 2025
FACULTY OF NURSING, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: To evaluate clinical applicability of immune mediator's interleukin-16, immunoglobulin E along with eosinophil count in diagnosing COVID-19 and determining its severity.
Patients And Methods: Materials and Methods: Cross-sectional case-control study was conducted at Al-Najaf General Hospital, Najaf, Iraq between March and August 2024. 120 participants: 60 confirmed COVID-19 cases and 60 healthy controls which matched cases in terms of age and sex.