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Angular cheilitis (AC) is associated with a variety of nutritional, systemic, and drug-related factors that may act exclusively or in combination with local factors. Establishing the underlying etiology of AC is required to appropriately focus treatment efforts.
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Int J Environ Res Public Health
July 2025
Department of Stomatology, Federal University of Parana, Curitiba 80210-170, Brazil.
This study presents the findings of an academic extension project focused on promoting oral health and diagnosing oral lesions in institutionalized elderly individuals. The project involved visits by students and faculty to two nursing homes in southern Brazil. Data collection included extraoral and intraoral clinical examinations and educational activities such as lectures and the distribution of printed materials on oral and denture hygiene.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
June 2025
Department of Oral Medicine & Radiology, Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, India.
Background: Psoriasis is a prevalent chronic inflammatory disorder that affects multiple systems. While the skin and joint symptoms of this condition are well established, the existence of oral manifestations associated with psoriasis is still debated.
Aim: The aim of our study is to determine the presence of oral abnormalities in patients with severe psoriasis and their association with the clinical characteristics of the disease.
This case report describes the emergence of oral immune-related adverse events following the administration of pembrolizumab, an immune checkpoint inhibitor (ICI), for cutaneous melanoma. The affected patient developed drug-induced oral lichenoid hypersensitivity reactions, oral candidiasis, and angular cheilitis that were successfully managed with topical dexamethasone and nystatin rinses and systemic fluconazole. Patients undergoing prolonged ICI therapy should be informed about the potential for oral complications and the need for close monitoring by oral healthcare providers.
View Article and Find Full Text PDFWorld J Clin Pediatr
June 2025
Faculty of Health Sciences, University Fernando Pessoa, Porto 4249-004, Portugal.
Background: Celiac disease (CD) is an autoimmune disease triggered by the ingestion of gluten in genetically predisposed individuals. It is more commonly diagnosed in children presenting typical clinical signs and symptoms but most of the CD patients diagnosed in the developed world are silent cases with no prominent gastrointestinal features. Thus, there are silent forms of the disease in which oral manifestations are the first sign.
View Article and Find Full Text PDFBMC Oral Health
June 2025
Department of Infectious Diseases and Allergology, Jan Kochanowski University, Kielce, Poland.
Background: Hepatitis C virus (HCV) infection, a systemic disease characterized by extrahepatic manifestations (EMs), affects approximately 50 million people worldwide. Recognizing EMs, which may involve multiple organs and systems, is crucial for timely diagnosis and effective antiviral therapy. Purpose of the study was to investigate extrahepatic symptoms occurring in the oral mucosa in HCV-infected patients.
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