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Objective: To investigate the results of reconstruction of hypopharyngeal circumferential and cervical esophageal defects with free jejunal transfer.
Methods: Retrospective review of 112 patients who underwent pharyngoesophageal reconstruction with free jejunal interposition. Analysis was confined to the patients with advanced hypopharyngeal, esophageal or recurrent laryngeal squamous cell cancer. Kaplan-Meier method was used to identify the accumulative survival rate.
Results: The free jejunal success rate was 94.6% (106/112). The pharyngocutaneous fistula rate and anastomoses narrow rate were 8.9% (10/112) and 12.5% (12/96) respectively. The perioperative mortality rate was 1.8% (2/112). Except 1 case of dead, 6 cases with flap failure and 2 cases with laryngeal preservation, other 103 cases had resumed oral feeding.
Conclusions: The success rate of free jejunal transplantation is high and free jejunal interposition is an ideal reconstruction method for patients who have hypopharyngeal circumferential and cervical esophageal defects after tumor resection.
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J Anim Sci
September 2025
Centre for Veterinary Systems Transformation and Sustainability, Clinical Department for Farm Animals and Food System Science, University of Veterinary Medicine Vienna, Vienna 1210, Austria.
It is helpful for diagnostic purposes to improve our current knowledge of gut development and serum biochemistry in young piglets. This study investigated serum biochemistry, and gut site-specific patterns of short-chain fatty acids (SCFA) and expression of genes related to barrier function, innate immune response, antioxidative status and sensing of fatty and bile acids in suckling and newly weaned piglets. The experiment consisted of two replicate batches with 10 litters each.
View Article and Find Full Text PDFCureus
August 2025
Liver Cancer Department, Binh Dan Hospital, Ho Chi Minh, VNM.
Duodenal perforation is a rare but harmful complication of endoscopic retrograde cholangiopancreatography (ERCP). Early diagnosis and appropriate management are critical to reduce morbidity and mortality. Four patients, aged 36 to 56 years, underwent ERCP for biliary obstruction due to choledocholithiasis or postoperative biliary stricture.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
National Academy of Medical Sciences, NAMS, Bir Hospital, Department of Radiodiagnosis, Kathmandu, Province-3, Nepal. Electronic address:
Introduction And Importance: Paraduodenal hernias (PDH) are the most common type of internal hernia, accounting for 53 % of cases, but remain a rare cause of intestinal obstruction overall. Left PDH, comprising about 75 % of all PDHs, can present with vague gastrointestinal symptoms or acute obstruction, with a high risk of strangulation and bowel ischemia. Early diagnosis and prompt surgical management are essential to reduce morbidity and mortality.
View Article and Find Full Text PDFEsophagus
September 2025
Department of Gastrointestinal Surgery, Institute of Science Tokyo, 1-5-45, Yushima, Bunkyo, Tokyo, 113-8510, Japan.
Background: Cervical esophageal cancer surgery can lead to postoperative gastric issues, impairing nutritional quality of life. This study aimed to compare larynx-preserving cervical esophagectomy with free jejunal graft interposition and subtotal esophagectomy with gastric pull-up reconstruction in terms of both short-term and long-term outcomes, with a particular focus on short-term nutritional parameters.
Methods: This single-institution, retrospective study included 87 patients who underwent surgery for cervical esophageal cancer between January 2011 and December 2021.
Animals (Basel)
August 2025
Department of Veterinary Medicine, School of Coastal Agriculture, Guangdong Ocean University, Zhanjiang 524088, China.
The rabbit industry urgently needs natural alternatives to maintain gut health. This need is growing due to the higher incidence of intestinal problems in antibiotic-free production systems. (Brazilian ginseng) is a medicinal plant rich in bioactive compounds.
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