Rapid urinary output normalization method using specific gravity.

Health Phys

Chalk River Laboratories, Atomic Energy of Canada Limited, Chalk River, Ontario K0J 1J0, Canada.

Published: August 2011


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Article Abstract

Spot urine samples are often taken for emergency radiobioassay to provide a quick dose assessment for contaminated individuals. The subsequent dosimetric analysis requires a urinary output normalization method to adjust spot sampling to daily urine excretion. A rapid specific gravity method that was developed for 24-h urinary output correction is described. Spot urine samples were collected from volunteers of different race, gender, and age to validate the normalization method. Results show that a specific gravity test is a fast, easy and robust method to correct the urine excretion in the event of a radiation emergency.

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http://dx.doi.org/10.1097/HP.0b013e318213be69DOI Listing

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