Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The performance of a microarray for the detection of extended-spectrum beta-lactamases was determined on a collection of 638 highly resistant members of the family Enterobacteriaceae collected from patients in 18 hospitals in The Netherlands. The microarray had a significantly higher specificity than the phenotypic assays. It also detects carbapenemases and characterizes the resistance genes, providing epidemiological insight.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147782 | PMC |
| http://dx.doi.org/10.1128/JCM.02087-10 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Virulence factors and outcomes in bacteremia caused by extended-spectrum β-lactamase-producing uropathogenic Escherichia coli ST131-H30Rx in a Swedish county.
BMC Infect Dis
September 2025
Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
Background: Escherichia coli ST131 and clade H30Rx are the most prevalent extended-spectrum β-lactamase-producing E. coli (ESBL-EC) causing bacteremia and urinary tract infections globally and in Sweden. Previous studies have linked ST131-H30Rx with septic shock and mortality, as well as prolonged carriage.
View Article and Find Full Text PDFEfficacy and activity of gepotidacin against bacterial uropathogens, including subsets with molecularly characterized resistance mechanisms and genotypes/epidemiological clones, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3).
Antimicrob Agents Chemother
September 2025
GSK, Collegeville, Pennsylvania, USA.
Gepotidacin, a novel, bactericidal, first-in-class triazaacenaphthylene antibacterial, was noninferior to nitrofurantoin in two pivotal trials (EAGLE-2 and EAGLE-3) in females with uncomplicated urinary tract infections (uUTIs). Using pooled data, gepotidacin activity and clinical efficacy were evaluated for subsets of molecularly characterized isolates in the microbiological Intent-to-Treat population. The subsets of isolates were characterized based on phenotypic/MIC criteria; all microbiological failure isolates were also characterized.
View Article and Find Full Text PDFThe investigation of bacteria in the oral of Trichomonas gallinae infected pigeons and the antibiotic resistance analysis of Klebsiella pneumoniae clinical isolates from farm pigeons in Shandong Province of China.
Poult Sci
September 2025
Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, China; Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai'an, Shandong, China. Electronic address:
While the global dissemination of extended-spectrum β-lactamases (ESBLs) in clinical isolates from various animals is well-documented, research on Klebsiella pneumoniae in Trichomonas gallinae-infected pigeons, particularly concerning antibiotic resistance genes in China, remains limited. This study aimed to investigate the relationship between oral harmful microbiota in pigeons and T. gallinae infection, as well as to isolate K.
View Article and Find Full Text PDFIdentification, and characterization of Escherichia coli O157:H7 from animal-derived foods in Hawassa and Yirgalem, Sidama Region, Ethiopia.
J Food Prot
September 2025
Faculty of Veterinary Medicine, Hawassa University, Hawassa Ethiopia, P.O.Box. 05.
Escherichia coli O157:H7 is a significant foodborne pathogen with global public health implications. This study, conducted from December 2022 to July 2023 in Hawassa and Yirgalem, Sidama Region, Ethiopia, assessed the prevalence, molecular identification, and antimicrobial resistance of E. coli O157:H7 in animal-derived foods.
View Article and Find Full Text PDFIntegrated metagenomic, culture-based, and whole genome sequencing analyses of antimicrobial resistance in wastewater and drinking water treatment plants in Barcelona, Spain.
Int J Hyg Environ Health
September 2025
ISGlobal, Barcelona, Spain; Faculty of Medicine and Health Sciences, University of Barcelona (UB), Barcelona, Spain; CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:
The misuse and overuse of antimicrobials drive the emergence of antimicrobial resistance (AMR), a critical global health concern. While wastewater treatment plants (WWTPs) are essential for removing microorganisms and contaminants, they also serve as hotspots for antibiotic-resistant bacteria (ARB) and antimicrobial resistance genes (ARGs), facilitating their persistence and dissemination. This study investigated AMR in two WWTPs and one drinking water treatment plant (DWTP) in the Baix Llobregat area of Barcelona, Spain.
View Article and Find Full Text PDF