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The establishment and spreading of biological populations depends crucially on population growth at low densities. The Allee effect is a problem in those populations where the per capita growth rate at low densities is reduced. We examine stochastic spatial models in which the reproduction rate changes across a gradient g so that the population undergoes a 2D-percolation transition. Without the Allee effect, the transition is continuous and the width w of the hull scales as in conventional (i.e., uncorrelated) gradient percolation, w ∝ g(-0.57). However, with a strong Allee effect the transition is first order and w ∝ g(-0.26).
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http://dx.doi.org/10.1103/PhysRevLett.106.128103 | DOI Listing |
Curr Opin Microbiol
September 2025
Cryptosporidiosis Laboratory, The Francis Crick Institute, London, United Kingdom. Electronic address:
The movement of molecules across the membranous barriers of a cell is fundamental to cellular homeostasis in every living organism. This vital process is facilitated through a mechanistically diverse class of proteins, collectively known as membrane transporters. Among these are so-called carrier proteins that can function in passive and active transport mechanisms.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Capturing the dynamic changes in patients' internal states as they approach death due to fatal diseases remains a major challenge in understanding individual pathologies and improving end-of-life care. However, existing methods primarily focus on specific test values or organ dysfunction markers, failing to provide a comprehensive view of the evolving internal state preceding death. To address this, we analyzed electronic health record (EHR) data from a single institution, including 8,976 cancer patients and 77 laboratory parameters, by constructing continuous mortality prediction models based on gradient-boosting decision trees and leveraging them for temporal analyses.
View Article and Find Full Text PDFEpigenomics
September 2025
College of Physical Education, Yangzhou University, Yangzhou, China.
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking objective biomarkers for early diagnosis. DNA methylation is a promising epigenetic marker, and machine learning offers a data-driven classification approach. However, few studies have examined whole-blood, genome-wide DNA methylation profiles for ASD diagnosis in school-aged children.
View Article and Find Full Text PDFBackground And Aims: Trait-based approaches have advanced our understanding of plant strategies, yet they often focus on leaf-level traits, overlooking the functional roles of stem anatomy and twig characteristics. We investigated intraspecific trait variation in Salix flabellaris, an alpine dwarf shrub, along climatic gradients in the Himalayas. Our goal was to identify distinct axes of trait variation related to stem, twig, and leaf traits, assess their environmental drivers, and evaluate population-specific growth responses to recent climate change.
View Article and Find Full Text PDFCureus
August 2025
Respiratory Medicine, Dartford and Gravesham NHS Trust, Dartford, GBR.
Pressure-dependent pneumothorax is an under-recognized but clinically significant phenomenon that complicates pleural fluid drainage, particularly in patients with non-expandable lungs due to malignancy or chronic pleural fibrosis. Unlike pressure-independent pneumothorax, this condition arises from the pronounced transpleural pressure gradient generated during therapeutic thoracentesis or chest drainage. This negative pressure transiently distorts the visceral pleura, allowing air to enter the pleural space until an equilibrium is reached.
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