Dot matrix pairwise sequence comparison.

CSH Protoc

Published: December 2007


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

INTRODUCTIONA dot matrix analysis is primarily a method for comparing two sequences to look for possible alignment of characters between the sequences. The method is also used for finding direct or inverted repeats in protein and DNA sequences, and for predicting regions in RNA that are self-complementary and that, therefore, have the potential of forming secondary structure through base-pairing.

Download full-text PDF

Source
http://dx.doi.org/10.1101/pdb.top31DOI Listing

Publication Analysis

Top Keywords

dot matrix
8
matrix pairwise
4
pairwise sequence
4
sequence comparison
4
comparison introductiona
4
introductiona dot
4
matrix analysis
4
analysis method
4
method comparing
4
comparing sequences
4

Similar Publications

Nitrosamines are genotoxic, mutagenic impurities and are widely encountered in the global landscape of the pharmaceutical industry. There is a need for rapid detection of nitrosamines in a pharmaceutical product. Here, we report the synthesis of carbon quantum dots (CQDs) using a readily available carbon precursor.

View Article and Find Full Text PDF

Background: Spiny mice (Acomys sp.) have a unique ability of scarless regeneration. Therefore, the transfer of models used in convenient laboratory mice to study fibrosis could be a prospective approach, enabling the identification of novel antifibrotic therapies.

View Article and Find Full Text PDF

Colloidal quantum dots (QDs) are semiconductor crystals a few nanometers in size. Due to their vibrant colors and unique photoluminescence (PL), QDs are widely utilized in displays, where barrier films provide essential shielding. However, one of the primary challenges of QD applications remains achieving sufficient robustness while keeping costs low.

View Article and Find Full Text PDF

The use of highly fluorescent quantum dot labels in lateral flow test strips enhances sensitivity of these rapid, facile and popular handheld diagnostic devices over traditional colloidal gold or latex particle labels. In this work, we demonstrate apparent detection limits of 1.25 ppb (ng/ml) for the important foodborne biotoxin staphylococcal enterotoxin B (SEB) in chicken rinsate and 78 ppb (ng/ml) in whole milk both by visual and objective fluorometer readings with optimized lateral flow (LF) red quantum dot-based test strips in 15 min.

View Article and Find Full Text PDF

Invadosomes as "shape-shifters" of cellular maturation: insights from megakaryocytes.

Front Cell Dev Biol

August 2025

Unité de Biologie Moléculaire, Cellulaire et du Développement (MCD, UMR 5077), Centre de Biologie Intégrative (CBI, FR 3743), Université de Toulouse, CNRS, UPS, Toulouse, France.

Invadosomes are a family of subcellular actin-based structures essential for cell-extracellular matrix (ECM) interaction and remodeling. In non-invasive cells, they are referred to as podosomes, which enable adhesion, migration, and ECM remodeling via secretion of metalloproteinases or mechano-traction. In invasive tumoral cells, these structures are called invadopodia due to their function.

View Article and Find Full Text PDF