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Objective: To assess the influence of a non-pharmacological intervention, consisting of a diet low glycemic index (GI) for a period of six months on metabolic control and anthropometric parameters in patients with type 1 diabetes mellitus.
Subjects And Methods: Ninety-six type 1 diabetic patients underwent an anthropometric, biochemical and dietary assessment before and six months after the prescription of diet based on the glycemic index.
Results: After six months we observed a decrease in A1C levels (9,8 ± 2,26% vs. 9,1 ± 2.16%; p = 0,023) and increase in body weight (61,3 ± 11,68 kg vs. 62,8 ± 12,07 kg; p = 0,04).
Conclusion: A low GI diet improved glycemic control in patients with DM1. Further studies with longer time of follow-up are needed to assess if patients' adherence to this kind of diet influences the maintenance of glycemic control.
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http://dx.doi.org/10.1590/s0004-27302010000900005 | DOI Listing |
Br J Nutr
September 2025
Systematic Review and Meta-Analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Although numerous clinical studies suggest that ginseng supplementation may benefit cardiovascular disease (CVD) risk factors, results remain inconclusive. This systematic review and meta-analysis evaluated the effects of ginseng supplementation on CVD-related risk factors. Relevant studies were identified through electronic searches in Embase, Web of Science, Scopus, PubMed, and CENTRAL up to August 2024.
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September 2025
Department of Neonatal Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Background: Children hospitalized for surgery face malnutrition risks. This study assessed nutritional risk and status in hospitalized neonatal surgical patients using a modified Screening Tool for the Assessment of Malnutrition in Pediatrics (STAMP) combined with anthropometry.
Methods: A retrospective analysis of neonatal surgical patients from December 2020 to October 2024 was conducted at a children's hospital, utilizing the modified STAMP and anthropometric measurements.
Indian J Endocrinol Metab
August 2025
Research and Publication Division, EuGEF Research Foundation, Chattogram, Bangladesh.
Introduction: Cationic trypsinogen () gene mutation is responsible for hereditary pancreatitis (HP) with clinical outcomes like abdominal pain, diabetes mellitus and pancreatic cancer. The present study aims to screen () gene polymorphism in the Bangladeshi population, categorized as normal glucose tolerant (NGT), prediabetes (PD) and type 2 diabetes (T2D).
Methods: Blood was collected from the study subjects with overnight fasting (8-10 h), and 2 h after 75 g glucose intake orally.
Front Biosci (Landmark Ed)
August 2025
Division of Biochemistry and Molecular Biology, Siberian State Medical University, Ministry of Health of the Russian Federation, 634050 Tomsk, Russia.
Background: Sarcopenia is a complex, multifactorial condition characterized by progressive loss of muscle mass, strength, and function. Despite growing awareness, the early diagnosis and pathophysiological characterization of this condition remain challenging due to the lack of integrative biomarkers.
Objective: This study aimed to conduct a comprehensive multilevel profiling of clinical parameters, immune cell phenotypes, extracellular vesicle (EV) signatures, and biochemical markers to elucidate biological gradients associated with different stages of sarcopenia.
Mol Nutr Food Res
September 2025
Department of Clinical Medicine and Surgery, Physiology Unit, University of Naples "Federico II", Napoli, Italy.
This study evaluated the effect of a nutraceutical supplementation (NS) and Mediterranean hypocaloric diet (MHD) on hepatic steatosis indices (HSIs), γ-glutamyl transferase (γGT), and lipid profile in adults with hyperlipidemia and nonalcoholic fatty liver disease (NAFLD). In vitro study on HepG2 cells explored potential molecular mechanisms. A retrospective study was conducted on 45 overweight/obese subjects (19 M) prescribed MHD with/without NS.
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