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The beta-rhizobium Cupriavidus taiwanensis forms indeterminate nodules on Mimosa pudica. C. taiwanensis bacteroids resemble free-living bacteria in terms of genomic DNA content, cell size, membrane permeability, and viability, in contrast to bacteroids in indeterminate nodules of the galegoid clade. Bacteroid differentiation is thus unrelated to nodule ontogeny.
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http://dx.doi.org/10.1128/AEM.02358-10 | DOI Listing |
J Am Soc Cytopathol
July 2025
Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Introduction: Molecular testing on thyroid fine needle aspirations with indeterminate cytology is integral to patient management. The aim of this study was to investigate the risk of malignancy in nodules diagnosed as Bethesda category IV, follicular neoplasm (FN), with and without cytologic atypia.
Methods: A total of 186 thyroid fine needle aspirations classified as Bethesda category IV (FN) were identified, and were categorized as FN with cytologic atypia or without cytologic atypia.
Biomedicines
August 2025
Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Molecular testing is most commonly performed in evaluation of thyroid nodules with indeterminate Fine Needle Aspiration Biopsy (FNAB) results. However, in clinical practice, thyroidectomy may still be pursued in patients who present with clear clinical indications despite a benign molecular test result. The aim of this study is to identify clinical factors that influence the decision to proceed with surgery in the presence of a benign molecular test result.
View Article and Find Full Text PDFRecenti Prog Med
September 2025
Dipartimento di Medicina, chirurgia e odontoiatria, Università di Salerno, Baronissi (Salerno).
Nodular goiter is a very frequent occurrence that rarely requires surgical treatments. Only a few of these nodules are the site of carcinoma which requires surgery. It is therefore necessary to precisely determine the nature of the nodule.
View Article and Find Full Text PDFUpdates Surg
August 2025
Department of General and Specialist Surgery, Sapienza University of Rome, Viale del Policlinico, 155, 00161, Rome, Italy.
Indeterminate thyroid cytology presents a significant diagnostic challenge, often leading to difficult treatment decisions for both physicians and patients. Effective communication of these uncertainties is crucial, especially in a surgical setting, where decisions can have long-lasting impacts. This is particularly important for younger surgeons who may lack extensive clinical experience.
View Article and Find Full Text PDFClin Endocrinol (Oxf)
August 2025
Department of Endocrinology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Introduction: Noninvasive follicular thyroid neoplasia with papillary-like nuclear characteristics (NIFTP) is characterised by an indolent behaviour and was defined in 2016 to avoid overtreatment in differentiated thyroid cancer (DTC).
Objectives: To report the clinicopathological characteristics and outcomes of patients with NIFTP treated at a Chilean centre between 2016 and 2023.
Design: Observational retrospective study.