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While "natural history" is practically synonymous with the name of Buffon, the term itself has been otherwise overlooked by historians of science. This essay attempts to address this omission by investigating the meanings of "physique," "natural philosophy," and "history," among other terms, with the purpose of understanding Buffon's actual objectives. It also shows that Buffon never claimed to be a Newtonian and should not be considered as such; the goal is to provide a historical analysis that resituates Buffon's thought within his own era. This is done, primarily, by eschewing the often-studied question of time in Buffon. Instead, this study examines the nontemporal meanings of the word "history" within the naturalist's theory and method. The title of his Natural History is examined both as an indicator of the kind of science that Buffon was hoping to achieve and as a source of great misinterpretation among his peers. Unlike Buffon, many of his contemporaries actually envisioned the study of nature from a Baconian perspective where history was restricted to the mere collection of facts and where philosophy, which was the implicit and ultimate goal of studying nature, was seen, at least for the present, as unrealizable. Buffon confronts this tendency insofar as his Histoire naturelle claims to be the real physique that, along with describing nature, also sought to identify general laws and provide clear insight into what true knowledge of nature is or should be. According to Buffon, history (both natural and civil) is not analogous to mathematics; it is a nonmathematical method whose scope encompasses both nature and society. This methodological stance gives rise to the "physicization" of certain moral concepts--a gesture that was interpreted by his contemporaries as Epicurean and atheist. In addition, Buffon reduces a number of metaphysically tainted historical concepts (e.g., antediluvian monuments) to objects of physical analysis, thereby confronting the very foundation of natural theology. In Buffon, as this essay makes clear, natural history is paving the way for a new physique (science of natural beings), independent from mathematics and from God, that treats naturalia in a philosophical and "historical" manner that is not necessarily "temporal."
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http://dx.doi.org/10.1086/652688 | DOI Listing |
Best Pract Res Clin Haematol
September 2025
Department of Personalized Medicine and Rare Diseases, Medfuture Institute for Biomedical Research - Department of Hematology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Hematology, Ion Chiricuta Cancer Center, Cluj Napoca, Romania. Electronic address:
Plasma cell myeloma (multiple myeloma) is a blood cancer characterized by the clonal proliferation of plasma cells in the bone marrow. Treatment strategies evolve year by year, new drugs getting Food and Drug Administration (FDA)-approved each year. Chimeric antigen receptor (CAR) therapies are an advanced form of immunotherapy that engineer T cells to recognize and destroy cancer cells.
View Article and Find Full Text PDFJ Am Soc Echocardiogr
September 2025
Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Inge Lehmannsvej 7, 2100 Copenhagen, Denmark. Electronic address:
Introduction: The natural history of bicuspid aortic valve (BAV) remains inadequately characterized, leaving uncertainties regarding whether associated aortic dilatation arises from an inherent susceptibility or primarily results from altered flow dynamics across the aortic valve. We aimed to describe the evolution of valve function and aortic dilatation at preschool-age in children diagnosed with BAV neonatally.
Methods: The population study, Copenhagen Baby Heart Study (n >25,000) performed in 2016-2018, diagnosed 196 newborns (0.
Acta Trop
September 2025
Laboratório de Parasitologia Médica e Biologia de Vetores, Faculdade de Medicina, Universidade de Brasília, DF, Brasil. Electronic address:
Phlebotomine sand flies are known vectors of Leishmania spp. to mammals, but also may transmit Sauroleishmania, and Trypanosoma spp. to reptiles and amphibians.
View Article and Find Full Text PDFEnviron Sci Technol
September 2025
State Key Laboratory of Regional and Urban Ecology, Ningbo Observation and Research Station, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China.
Microplastics (MPs) are raising significant global concerns due to their environmental impacts. While most studies have focused on the effects of individual MP types, MPs in natural environments typically coexist as multiple types, and their combined effects remain poorly understood. In this study, we conducted a microcosm experiment with four levels of MP diversity (0, 1, 3, and 5 types) to investigate the effects of MP diversity on soil ecosystem functions using metagenomic sequencing.
View Article and Find Full Text PDFJ Bone Miner Res
September 2025
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
Autosomal Dominant Osteopetrosis (ADO) is a rare, osteosclerotic disorder usually caused by missense variants in the CLCN7 gene, resulting in impaired osteoclastic bone resorption. Penetrance is incomplete and disease severity varies widely, even among relatives within the same family. Although ADO can cause visual loss, osteonecrosis, osteomyelitis, and bone marrow failure, the most common complication of ADO is fracture.
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