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Article Abstract
We synthesized a range of PQS (Pseudomonas quinolone signal; 2-heptyl-3-hydroxy-4(1H)-quinolone) analogues and tested them for their ability to stimulate MvfR-dependent pqsA transcription, MvfR-independent pyoverdine production, and membrane vesicle production. The structure-activity profile of the PQS analogues was different for each of these phenotypes. Certain inactive PQS analogues were also found to strongly synergize PQS-dependent pyoverdine production.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897350 | PMC |
| http://dx.doi.org/10.1128/JB.00081-10 | DOI Listing |
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