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Article Abstract
Background: Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood.
Case Presentation: We report the first case of CHIKV infection with chronic associated rheumatism in a patient who developed progressive erosive arthritis with expression of inflammatory mediators and persistence of specific IgM antibodies over 24 months following infection.
Conclusions: Understanding the specific features of chikungunya virus as well as how the virus interacts with its host are essential for the prevention, treatment or cure of chikungunya disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803790 | PMC |
| http://dx.doi.org/10.1186/1471-2334-9-200 | DOI Listing |
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