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Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges. | LitMetric

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Article Abstract

Four new dimeric pyrrole-2-aminoimidazole alkaloids have been isolated from the Pacific marine sponges Agelas cf. mauritiana and Phakellia sp. They include the unusual C2 symmetrical benzosceptrins A (4) and B (5), which each possess a unique benzocyclobutane skeleton and nagelamides S (6) and T (7). Their structures and relative configuration were elucidated from spectroscopic data. Plausible biogenetic paths for these compounds are also proposed in this paper.

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http://dx.doi.org/10.1021/ol901946hDOI Listing

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