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We have developed a computer-aided diagnosis (CAD) system to detect pulmonary nodules on thin-slice helical computed tomography (CT) images. We have also investigated the capability of an iris filter to discriminate between nodules and false-positive findings. Suspicious regions were characterized with features based on the iris filter output, gray level and morphological features, extracted from the CT images. Functions calculated by linear discriminant analysis (LDA) were used to reduce the number of false-positives. The system was evaluated on CT scans containing 77 pulmonary nodules. The system was trained and evaluated using two completely independent data sets. Results for a test set, evaluated with free-response receiver operating characteristic (FROC) analysis, yielded a sensitivity of 80% at 7.7 false-positives per scan.
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http://dx.doi.org/10.1016/j.compbiomed.2009.07.005 | DOI Listing |
J Fish Biol
September 2025
Bonefish and Tarpon Trust, Miami, Florida, USA.
Bonefish Albula spp. in the Western Atlantic have historically been morphometrically and phenotypically indiscernible. We used biofluorescence in two sympatric, cryptic bonefish species, Albula goreensis and Albula vulpes, to develop a rapid and inexpensive in situ survey for species identification that can be used by managers and recreational anglers.
View Article and Find Full Text PDFMol Autism
August 2025
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Autism Research and Intervention Center of Excellence, University Hospital Frankfurt, Goethe-University, Deutschordenstraße 50, 60528, Frankfurt Am Main, Germany.
Background: Sensory processing requires selectivity to salient sensory input. Many autistic individuals report different sensory processing, which has been associated with altered sensory selectivity. The locus-coeruleus norepinephrine (LC-NE) system modulates the neuronal gain of sensory input, which represents a neurophysiological mechanism of sensory selectivity.
View Article and Find Full Text PDFSensors (Basel)
July 2025
Department of Surgery, University of Manitoba Max Rady College of Medicine, Winnipeg, MB R3E 0W2, Canada.
Pupillometry is commonly used to evaluate cognitive effort, attention, and facial expression response, offering valuable insights into human performance. The combination of eye tracking and facial expression data under the iMotions platform provides great opportunities for multimodal research. However, there is a lack of standardized pipelines for managing pupillometry data on a multimodal platform.
View Article and Find Full Text PDFJ Opt Soc Am A Opt Image Sci Vis
May 2025
This study aimed to investigate how variation in iris color, along with ethnic origin, affects color vision. For color vision deficiency screening, the Ishihara, D-15, and D-15d tests were employed. Chromatic discrimination was assessed in normal trichromats using the Cambridge Colour Test (CCT).
View Article and Find Full Text PDFParasite
July 2025
Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Beirut Campus, P.O. Box 13-5053, Chouran, 1102 2801 Beirut, Lebanon.
Cutaneous leishmaniasis presents a significant challenge to public health due to its diverse clinical manifestations, resistance development, and treatment-related adverse effects. Here, we examined the efficacy of ivermectin, moxidectin (MOX), afoxolaner, and permethrin against all stages of Leishmania tropica and THP-1 cells. We also assessed the potential for resistance acquisition after 15 rounds of artificial selection.
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