Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objectives: To ascertain which variables of bladder urothelial carcinoma (UC) might be useful in predicting either UC involving the prostate (UCP) or incidental prostate adenocarcinoma in radical cystoprostatectomy specimens.
Methods: The bladder and whole-mount prostate sections of 248 radical cystoprostatectomy specimens were reviewed. Stepwise discriminant analysis was used to predict UCP or incidental prostate adenocarcinoma.
Results: UCP was present in 94 patients (37.9%). UC originated from the prostatic urethra and periurethral ducts in 78 (31.45%), and isolated direct extension of UC from the bladder was present in 16 patients (6.45%). The periurethral ducts coexisted with direct extension of bladder UC in 11 patients (4.4%). Prostate adenocarcinoma was identified in 123 patients (49.6%). Carcinoma in situ and high-grade urothelial papillary carcinoma were seen in 8 (3.2%) and 5 (2.0%) patients, respectively. In 57 (23%), 64 (25.8%), and 87 (35.1%) patients, UC had invaded the subepithelial connective tissue, muscularis propria, and perivesical tissue, respectively. UC was multifocal in 53 patients (21.4%). The tumor was in the trigone and bladder neck in 160 patients (64.5%). Of the 248 patients, 98 (39.5%) had a history of recurrence. Stepwise discriminant analysis selected 3 variables of bladder UC (previous recurrence and location and number of foci) and correctly predicted the group in 72.2% of patients without and with UCP. Discriminant analysis selected 2 variables of bladder UC (focality and previous recurrence) and correctly predicted the group in 57.7% of patients without and with prostate adenocarcinoma.
Conclusions: Our approach can identify bladder UC variables that could guide urologists in the selection of the most appropriate surgical procedure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.urology.2009.03.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Prostate sparing radical cystectomy and neobladder: institutional long-standing qualified consideration.
J Egypt Natl Canc Inst
September 2025
National Cancer Institute of Cairo University, Giza, Egypt.
Objectives: To balance the extended functional urinary voiding and morbidity outcomes amid Ileal W and Y-shaped contrasted to spherical ileocoecal (IC) orthotopic bladders subsequent prostate-sparing radical cystectomy (PRC) versus standard radical cystoprostatectomy (RC).
Material And Methods: Two hundred eight male bladder cancer patients were grouped into 98 RC followed by 43-W, 31-Y, and 23-IC in comparison to 110 PRC followed by 35-W, 37-Y, and 38-IC. The functional voiding outcomes were determined by detailed patients' interview and urodynamic studies (UDS).
Urothelial carcinoma arising in orthotopic ileal neobladder reconstruction: A case report.
World J Clin Cases
September 2025
Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.
Background: An ileal neobladder is a standardized form of urinary diversion that provides acceptable outcomes in terms of long-term quality of life. Urothelial carcinomas (UCs) arising in the ileal neobladder are extremely rare, and few reports on this have been published in the English language.
Case Summary: We report a case of UC that developed in the ileal neobladder of a 63-year-old man.
Silent but Invasive: A Case Report of a Sarcomatoid Bladder Carcinoma in a 29-Year-Old Male Presenting As Vesico-Cutaneous Fistula Without Hematuria.
Cureus
July 2025
Urology and Renal Transplant Surgery, Sawai Man Singh Medical College, Jaipur, IND.
Sarcomatoid urothelial carcinoma (SUC) is a rare and aggressive variant of urinary bladder cancer and is associated with a poor prognosis. This case report presents the unusual case of a 29-year-old male who presented with a vesicocutaneous fistula causing continuous suprapubic urine leakage for four months following a previous bladder surgery for a vesical calculus. This patient had no history of hematuria, which is a common symptom of bladder cancer.
View Article and Find Full Text PDFManaging bladder tumor with long-segment anterior urethral stricture: Perineal urethrostomy as a critical surgical solution.
Radiol Case Rep
October 2025
Urology A Department, University Hospital Ibn Sina, Rabat, Morocco.
Bladder tumors complicated by anterior urethral strictures present unique management challenges, as strictures often prevent standard transurethral resection of bladder tumors (TURBT). While advances in endoscopic techniques have reduced the frequency of alternative approaches, perineal urethrostomy remains a valuable option in select cases. A 56-year-old male with a history of chronic tobacco use and recurrent, inadequately treated urethritis presented with clot-forming gross hematuria.
View Article and Find Full Text PDFRisk Factors for Sigmoid Colonic Anastomosis: A Comparative and Cross-Sectional Analysis.
Ther Clin Risk Manag
August 2025
Department of General Surgery, Erciyes University, Kayseri, Turkey.
Objective: To evaluate the anastomotic leakage (AL) rates in cancerous and non-cancerous intestinal anastomoses and analyze the general risk factors for AL.
Methods: The primary endpoint of this study is to investigate whether there is a difference in terms of AL between patients who underwent sigmoid colon resection + colorectal anastomosis due to primary colon cancer (Group 1) and patients with a completely healthy colorectal region who underwent sigmoid colon resection + colorectal anastomosis for use in the orthotopic bladder during radical cystoprostatectomy (Group 2). The secondary endpoint, considering all the patients, is to evaluate and investigate the risk factors affecting the AL rates.