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Objectives: Although fatigue after stroke is common, little is known about the effect of fatigue on functional outcomes in stroke patients. We, therefore, evaluated the influence of fatigue on functional outcomes after stroke.
Design: Forty consecutive outpatients were evaluated 32.7 +/- 27.4 mos after the onset of stroke. Poststroke fatigue was scored using the Fatigue Severity Scale, activity of daily living function was assessed using the Modified Barthel Index, motor function was assessed using the Motricity Index, and cognitive function was evaluated using the Korean-Mini Mental State Examination. The Beck Depression Inventory was used to assess depression, and patients were interviewed about sleeping problems.
Results: The average Fatigue Severity Scale score was 3.6 +/- 1.5 in stroke patients, with 12 patients (30.0%) having Fatigue Severity Scale scores >or=4 points. Twenty-two patients (55.0%) had depression, and 12 (30%) had sleeping problems. Fatigue Severity Scale score was significantly correlated with Beck Depression Inventory and sleep disturbance (P < 0.05) but was not significantly correlated with Modified Barthel Index, Motricity Index or Korean-Mini Mental State Examination.
Conclusions: We found that 30% of stroke victims had poststroke fatigue. Poststroke fatigue was not closely associated with motor function, activity of daily living, or cognitive function, but showed significant correlation with depression and sleeping problems. These findings emphasize the need for careful clinical screening of both fatigue and depression in individuals after stroke.
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http://dx.doi.org/10.1097/PHM.0b013e3181a0dae0 | DOI Listing |
Turk J Pediatr
September 2025
Department of Pediatric Hematology and Oncology, Batman Training and Research Hospital, Batman, Türkiye.
Background: Brucellosis is a zoonotic infection transmitted to humans by ingestion of contaminated unpasteurized dairy products or via direct or indirect contact with infected animals. It is characterized by nonspecific symptoms like fever and joint pain, and laboratory findings including anemia, leukopenia, thrombocytopenia, or rarely pancytopenia. Here we report a case of brucellosis with thrombocytopenia that did not improve despite anti-brucella treatment and required intravenous immunoglobulin treatment.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Social Science, Malawi Liverpool Wellcome Clinical Programme, Blantyre, Malawi.
Diarrhoea due to rotavirus remains a significant cause of child mortality in developing regions. Caregivers' perspectives on the social determinants of gastroenteritis and childhood vaccination, including the rotavirus vaccine, were explored through focus group discussions in Ethiopia (n = 6), Kenya (n = 14), and Malawi (n = 10), using a combination of thematic and framework analysis approaches. The results show that diarrhoea was perceived to be a burden in all three countries, particularly among infants, due to challenges in WASH (water, sanitation, and hygiene) infrastructures and poverty.
View Article and Find Full Text PDFActa Neurol Belg
September 2025
Neuroscience Research Australia, University of New South Wales, Sydney, Australia.
Objectives: Patients diagnosed with amyotrophic lateral sclerosis (ALS) typically describe symptoms of fatigue. Despite this frequency, the underlying mechanisms of fatigue are poorly understood, and are likely multifactorial. To help clarify mechanisms, the present systematic review was undertaken to determine the risk factors related to fatigue in ALS.
View Article and Find Full Text PDFClin Lab
September 2025
Background: Patients with epilepsy often require long-term antiepileptic medications, which can affect hematological parameters. Influenza (H1N1) infection is known to potentially cause thrombocytopenia. This case examines the clinical implications of a 29-year-old female patient with epilepsy who developed influenza and significant platelet reduction.
View Article and Find Full Text PDFEur J Anaesthesiol
September 2025
From the Department of Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Multidisciplinary Pain Centre, Ziekenhuis Oost-Limburg, Genk (WR, DM, IM, HS, ST), Department of Anaesthesiology, University Hospitals Leuven (WR, SR), Department of Cardiovascular Sciences, KU Leuven, Leuven (WR
Postoperative fatigue (POF) and perioperatively acquired muscle weakness (POAW) are significant yet often under-recognised interlinked postoperative complications that can significantly hinder postoperative recovery and diminish overall quality of life after surgery. Despite advancements in surgical and anaesthetic techniques and the widespread implementation of Enhanced Recovery After Surgery (ERAS) protocols, these conditions remain prevalent. In the weeks following surgery, reported incidences of fatigue of any severity range from 10% to as high as 90%, depending on the patient population.
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