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Pulmonary embolism (PE) is a fatal disease that is very rare in young people. A 21-year-old man developed PE because of a retroperitoneal tumor. The inferior vena cava (IVC) was obstructed by the tumor, and thrombus existed in the right common iliac vein. Thrombolysis and heparinization improved his symptoms prior to urgent tumor resection. A temporary IVC filter was inserted the day before the operation, but 8 h later fatal massive PE occurred. At autopsy, the retroperitoneal tumor was revealed as a metastatic choriocarcinoma. Prophylactic use of a temporary IVC filter might have paradoxically induced recurrence of massive PE in this case.
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http://dx.doi.org/10.1253/circj.cj-08-0448 | DOI Listing |
Urol Case Rep
September 2025
Austin Health, Heidelberg, VIC, Australia.
We report a 43-year-old man with de novo metastatic testicular seminoma complicated by paraplegia from spinal cord compression due to retroperitoneal lymphadenopathy. Urgent retroperitoneal biopsy confirmed seminoma and, after the patient declined neurosurgical intervention, systemic chemotherapy was promptly initiated prior to delayed orchidectomy. Post-chemotherapy orchidectomy histology revealed minimal viable tumour and serial imaging showed a residual retroperitoneal mass with low-grade uptake on FDG-PET.
View Article and Find Full Text PDFCureus
August 2025
College of Health Sciences, Universidad San Francisco de Quito, Quito, ECU.
Lattice radiotherapy (LRT) is a type of spatially fractionated radiation therapy (SFRT) that enables the delivery of ablative doses to specific internal regions of large tumoral lesions, while surrounding tissues and nearby critical structures receive significantly lower exposure. This technique relies on a spatial distribution strategy that allows dose levels of radiation to be applied within the tumor in a single session or, alternatively, over the course of five sessions. Over time, LRT has gained attention as a promising method for managing large tumors, especially in cases where conventional treatments may pose higher risks or be less effective, offering the benefit of reduced side effects.
View Article and Find Full Text PDFJ Surg Case Rep
September 2025
Department of Urology, The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, No. 6 of Qinren Road, Foshan 528000, Guangdong, People's Republic of China.
A 55-year-old female presented with left flank pain and ureteral obstruction. Imaging revealed a retroperitoneal mass suspicious for malignancy. Histopathology confirmed an inflammatory myofibroblastic tumor (IMT; anaplastic lymphoma kinase [ALK]-negative, mouse double minute 2 homolog-positive).
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Gynecology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Obesity is closely linked to an increased incidence of several gynecological conditions and poses significant challenges to their surgical management. Among these, endometrial cancer stands out due to its high prevalence in patients with elevated body mass index, with nearly 60% of those requiring primary surgical treatment classified as obese or morbidly obese. The coexistence of multiple comorbidities in this population contributes to a heightened risk of perioperative and postoperative complications.
View Article and Find Full Text PDFAnn Vasc Dis
August 2025
Department of Cardiovascular Surgery, Nara Prefecture General Medical Center, Nara, Nara, Japan.
Intravenous leiomyomatosis with intracardiac extension is a rare benign tumor originating from uterine smooth muscle. A 50-year-old woman presented with a cardiac mass 3 years after hysterectomy. Imaging revealed a tumor extending from the right internal iliac vein to the right atrium.
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