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We present the first case in which magnetic resonance imaging (MRI) has been utilized to rule out lesions compatible with acute pyelonephritis in kidneys from a cadaveric organ donor before transplanting them. A 40-year-old female underwent diagnosis of brain death following a septic shock. The ecotomography of the kidneys showed areas compatible with micro-abscesses raising the hypothesis of acute pyelonephritis. Our radiologist proposed to perform a bench-MRI (maintaining kidneys within the sterile preservation bags constantly on ice); this did not show lesions except little cysts not relevant by the clinical point of view. We transplanted kidneys without infective complications and results were very good.
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http://dx.doi.org/10.1093/ndt/gfn618 | DOI Listing |
JCEM Case Rep
October 2025
Henry Ford Providence Southfield Internal Medicine, Southfield, MI 48075, USA.
We report a 28-year-old woman with refractory hypoglycemia, hypotension, and profound fatigue found to have panhypopituitarism secondary to Sheehan syndrome. Although she had a remote history of postpartum hemorrhage marked by agalactia and secondary amenorrhea, her diagnosis was delayed until she developed an adrenal crisis in the setting of acute pyelonephritis. Comprehensive endocrine testing confirmed secondary adrenal insufficiency, central hypothyroidism, hypogonadotropic hypogonadism, and lactotroph failure; Magnetic resonance imaging demonstrated a partially empty sella consistent with remote pituitary infarction.
View Article and Find Full Text PDFRadiol Case Rep
November 2025
Department of Radiology, School of Medicine, 5th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Golestan, Iran.
Acute pyelonephritis is a common renal infection that can become life-threatening when complicated by structural abnormalities, resistant pathogens, or systemic comorbidities such as diabetes mellitus. While common complications include renal abscess and sepsis, spontaneous subcapsular hematoma is a rare but serious manifestation that requires prompt recognition and intervention. This article reports the case of a 54-year-old female with a history of diabetes mellitus, hypertension, and hyperlipidemia, who presented with fever, flank pain, vomiting, and gross hematuria.
View Article and Find Full Text PDFDiabetes Metab J
August 2025
Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Diabetes mellitus predisposes individuals to a broad spectrum of infections. People with diabetes face a 1.5- to 4-fold increased risk of both common and severe infections, and infections remain the leading cause of morbidity and mortality.
View Article and Find Full Text PDFPediatr Infect Dis J
August 2025
From the Division of Microbiology, Immunology and Glycobiology, Department of Laboratory Medicine, Lund University.
Background: Infections trigger complex immune responses, with conserved as well as disease-specific characteristics.
Methods: Proteomic screening technology and gene expression analysis were used here to define the immune response in infants, with their first episode of febrile urinary tract infection. Urine and peripheral blood samples were obtained at enrollment and at follow-up, after 6 months.
J Endourol
August 2025
Department of Surgery, Section of Urology, University of Manitoba, Winnipeg, Canada.
Previous studies have demonstrated the feasibility of bedside placement of ureteral stents in cases of acute ureteral obstruction. However, there is a lack of evidence comparing its efficacy to traditional stent placement in the operating room with fluoroscopy. We compared the clinical outcomes of bedside ureteral stent placement with the current standard of care.
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