Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Sixty-one non-repetitive Enterobacter cloacae ESBL producers were collected at the Amiens University Hospital in France. Eight beta-lactam resistance phenotypes (a-h) and three aminoglycoside resistance phenotypes (i-k) were identified among these isolates, and 32 different pulsotypes were observed. Of these 61 isolates, 37 were sequenced and found to harbor beta-lactamases with a pI of 5.9 (TEM-4), 6.5 (TEM-24), 7.8 (SHV-4), 8.2 (SHV-12), 8.4 (CTX-M-1) and 8.0 (CTX-M-9). Four imipenem-resistant ESBL-producing E. cloacae isolates did not express the 38kDa OMP, indicating that this resistance is associated with porin deficiency.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.resmic.2008.09.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Longitudinal molecular epidemiology of ceftriaxone-resistant enterobacterales in intra-abdominal and urinary tract infections: A decade-long SMART surveillance study in Taiwan (2009-2019).
J Microbiol Immunol Infect
August 2025
Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, And College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:
Background: Third-generation cephalosporin-resistant Enterobacterales is a recognized global concern. This study investigated the molecular epidemiology of β-lactamase genes and antimicrobial susceptibility patterns among ceftriaxone-resistant Enterobacterales causing intra-abdominal and urinary tract infections in Taiwan between 2009 and 2019.
Methods: Data from the SMART surveillance program were analyzed, including Enterobacterales isolates with ceftriaxone minimum inhibitory concentrations ≥4 μg/mL.
In Vitro synergy of Farnesyltransferase inhibitors in combination with colistin against ESKAPE bacteria.
PLoS One
September 2025
Faculty of Health, Institute of Pharmacology and Toxicology, Centre for Biomedical Education and Research (ZBAF), School of Medicine, Witten/Herdecke University, Witten, Germany.
The emergence of antibiotic resistance continues to pose a significant global challenge. Drug repurposing, wherein existing therapeutics are evaluated for new applications, offers a promising strategy to address this issue. Farnesyltransferase inhibitors (FTIs), initially developed for cancer therapy, have demonstrated antimicrobial activity against several gram-positive bacteria.
View Article and Find Full Text PDFBacillus toyonensis BAR1, a yellow-pigment producing endophyte of Berberis aristata DC: a potential source of bioactive and antimicrobial compounds.
Folia Microbiol (Praha)
September 2025
Department of Biotechnology and Genetic Engineering, Hazara University, Mansehra, Pakistan.
Herein, we report the isolation and characterization of an endophytic bacterium associated with the Berberis aristata roots to uncover bioactive compounds, particularly Antimicrobials, using submerged culture. The bacterial isolate was identified via 16S rDNA sequence analysis and characterized using morphological, microscopic, and biochemical techniques. It was identified as Bacillus toyonensis strain BAR1, a motile, gram-positive, halotolerant bacterium capable of producing yellow pigments.
View Article and Find Full Text PDFPrevalence, Clinical Characteristics, and Mortality Impact of Metallo-β-Lactamase-Producing Enterobacter Cloacae Complex Infections: A Retrospective Cohort Study.
J Glob Antimicrob Resist
September 2025
Division of Infectious Diseases, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address:
Background: Metallo-β-lactamase (MBL)-producing Enterobacter cloacae complex (ECC) is an emerging threat associated with limited treatment options and increased mortality. This study aimed to describe the clinical and molecular characteristics, risk factors, and outcomes of MBL-producing ECC infections in Taiwan.
Methods: We conducted a retrospective cohort study at a tertiary hospital in central Taiwan from July 2022 to December 2023.
Fatal Trichosporon asahii Fungemia Following Polymicrobial Bacteremia in a Non-neutropenic Elderly Patient: A Case Report.
Cureus
August 2025
Medical Mycology Research Center, Chiba University, Chiba, JPN.
species are known to cause disseminated infections in immunocompromised hosts, typically in patients with hematological malignancies undergoing chemotherapy and those with a history of antifungal use. This case report described a non-neutropenic 85-year-old male patient with fungemia following polymicrobial bacteremia. He presented with fever and disturbed consciousness and was admitted for sepsis (day 1).
View Article and Find Full Text PDF