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Article Abstract
Explorations of the S(1') subsite of ACE2 via modifications of the P(1') methylene biphenyl moiety of thiol-based metalloprotease inhibitors led to improvements in ACE2 selectivity versus ACE and NEP, while maintaining potent ACE2 inhibition.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127737 | PMC |
| http://dx.doi.org/10.1016/j.bmcl.2008.01.046 | DOI Listing |
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