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Background: The radiofrequency unilateral interruption of the spinothalamic tract at the level of the superior colliculi in the mesencephalon is one of the more ancient functional neurosurgery operation. Based on the literature review our aim is to consider the potential role of this old intervention in the modern neurosurgical armamentarium against cancer pain taking into account the evolution of the operative technique and the emergence of alternative approaches.
Material And Method: We reviewed the literature in order to analyse the anatomical targeting of the spinothalamic tract, the technical strategies, the efficacy on pain, the morbi-mortality the comparison of the safety efficacy ratio with other surgical technics depending on the indications.
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Functional disorders of the upper digestive tract, including functional dyspepsia and irritable bowel syndrome with predominant gastric symptoms, represent conditions that are highly prevalent in the general population and are associated with a marked impairment of patients' quality of life. Functional dyspepsia, characterised by symptoms such as epigastric pain, early satiety and bloating, in the absence of detectable structural abnormalities, is commonly divided into two subtypes: postprandial distress syndrome and epigastric pain syndrome, as described in the Rome IV diagnostic criteria. Although the pathogenesis of these disorders is not completely understood, it is believed that there is a complex interaction between altered gastrointestinal motility, visceral hypersensitivity, gut dysbiosis and dysfunction in the central modulation of visceral signals.
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