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Article Abstract
Aim: To investigate the protein and mRNA expression of semaphorin 6D in gastric carcinoma and its significance.
Methods: The protein and mRNA expression of semaphorin 6D was detected by semi-quantitative reverse transcription PCR and Western blotting respectively in 30 cases of gastric carcinoma and normal gastric mucosa.
Results: The protein and mRNA expression of semaphorin 6D in gastric carcinoma was significantly higher than that in normal gastric mucosa (0.24 +/- 0.06 vs 0.19 +/- 0.07, 0.26 +/- 0.09 vs 0.20 +/- 0.10, P < 0.05).
Conclusion: Semaphorin 6D may play an important role in the occurrence and development of gastric carcinoma, and is related to tumor angiogenesis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087504 | PMC |
| http://dx.doi.org/10.3748/wjg.v12.i45.7388 | DOI Listing |
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