98%
921
2 minutes
20
A single institution is not well positioned to manage the process of tissue donations to maximize utility and minimize the costs associated with such transactions. The proposed creation of a 'hub' organization to service the needs and demands associated with tissue procurement and utilization is outlined. The case of Arizona is used as a case study for the proposed model building on existing network in tissue donation and research. The proposed model would consequently be viewed as legitimate by various network stakeholders, including the general public. Finally, the proposed hub-network would be better able to manage the donation, procurement, storage, preservation, distribution, and use of human tissues for all of the potential uses in a single state.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1258/095148406778951448 | DOI Listing |
Nat Commun
October 2023
SANKEN (The Institute of Scientific and Industrial Research), Osaka University, Mihogaoka 8-1, Ibaraki, Osaka, 567-0047, Japan.
Sensors (Basel)
November 2018
Department of Information and Communications Engineering, Sunchon National University, Jeollanam-do 57922, Korea.
Crop diseases cannot be accurately predicted by merely analyzing individual disease causes. Only through construction of a comprehensive analysis system can users be provided with predictions of highly probable diseases. In this study, cloud-based technology capable of handling the collection, analysis, and prediction of agricultural environment information in one common platform was developed.
View Article and Find Full Text PDFBiometrics
September 2016
Division of Biostatistics, School of Medicine, New York University 650 First Avenue, New York, New York 10016, U.S.A..
The next-generation sequencing data, called high-throughput sequencing data, are recorded as count data, which are generally far from normal distribution. Under the assumption that the count data follow the Poisson log-normal distribution, this article provides an L1-penalized likelihood framework and an efficient search algorithm to estimate the structure of sparse directed acyclic graphs (DAGs) for multivariate counts data. In searching for the solution, we use iterative optimization procedures to estimate the adjacency matrix and the variance matrix of the latent variables.
View Article and Find Full Text PDFBiochem Biophys Res Commun
May 2013
State Key Laboratory of Molecular Oncology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, PR China.
Whether the heterogeneity in tumor cell morphology and behavior is the consequence of a progressive accumulation of genetic alterations or an intrinsic property of cancer-initiating cells established at initiation remains controversial. The hypothesis of biological predetermination in human cancer was proposed many years ago and states that the biological potency of cancer cells is predestinated in the precancerous stage. The present study aimed to investigate whether the aberrant molecular events occurring in initial cancer stages could eventually influence colorectal cancer (CRC) progression.
View Article and Find Full Text PDFHealth Serv Manage Res
November 2006
TRIA Orthopaedic Research Institute, Minneapolis, MN 55431, USA.
A single institution is not well positioned to manage the process of tissue donations to maximize utility and minimize the costs associated with such transactions. The proposed creation of a 'hub' organization to service the needs and demands associated with tissue procurement and utilization is outlined. The case of Arizona is used as a case study for the proposed model building on existing network in tissue donation and research.
View Article and Find Full Text PDF