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Edward H. Angle dominated orthodontic armamentarium, diagnosis and treatment planning for almost a half century until Charles Tweed successfully challenged his mentor's nonextraction mantra. The ensuing diagnostic regimen used by Tweed, however, proved to have serious limnitations and clearly resulted in the extraction of too many teeth. This caused a subsequent deterioration of soft tissue appearances of patients that neither they nor their doctors liked. This article will describe and illustrate how new expansion techniques differ qualitatively from those of Angle, and how these techniques offer patients and doctors less invasive and more comfortable therapies which do not jeopardize facial appearances.
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JMIR Cancer
September 2025
Cancer Patients Europe, Rue de l'Industrie 24, Brussels, 1000, Belgium.
Background: Breast cancer is the most common cancer among women and a leading cause of mortality in Europe. Early detection through screening reduces mortality, yet participation in mammography-based programs remains suboptimal due to discomfort, radiation exposure, and accessibility issues. Thermography, particularly when driven by artificial intelligence (AI), is being explored as a noninvasive, radiation-free alternative.
View Article and Find Full Text PDFJMIR Public Health Surveill
September 2025
Center of Indigenous Health Care, Department of Community Health, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.
Background: The COVID-19 pandemic has devastated economies and strained health care systems worldwide. Vaccination is crucial for outbreak control, but disparities persist between and within countries. In Taiwan, certain indigenous regions show lower vaccination rates, prompting comprehensive inquiries.
View Article and Find Full Text PDFSci Adv
September 2025
Sol Price School of Public Policy, University of Southern California, Los Angeles, CA, USA.
Antimicrobial resistance is largely driven by overuse of antibiotics, which is particularly common in low- and middle-income countries. We combine provider knowledge assessments and over 2000 anonymous standardized patient visits to providers in India to examine why they overprescribe antibiotics for pediatric diarrhea and figure out how to reduce overprescribing. Seventy percent of providers prescribed antibiotics without indication of bacterial infection.
View Article and Find Full Text PDFTher Drug Monit
September 2025
Departments of Pharmacology, and.
Background: Fluconazole-tacrolimus interactions occur, but the additional effect of ritonavir is emphasized here, underscoring the need for careful prescription reconciliation in renal transplant recipients living with HIV-AIDS to prevent accidental ritonavir coadministration and inadvertent tacrolimus toxicity. The findings provide valuable insight for therapeutic drug monitoring (TDM) specialists. Patient informed consent was obtained for publication of the anonymized data.
View Article and Find Full Text PDFJ Palliat Med
September 2025
Section of Palliative Care, Department of Medicine, Stanford School of Medicine, Stanford, California, USA.
Communication skills training alone has shown limited impact on improving the frequency and quality of serious illness conversations (SICs). Implementing structured support strategies may enhance both adoption and sustained use in clinical practice. Retrospective review of the impact of Serious Illness Care Program (SICP) training and implementation in outpatient and inpatient settings at a single academic center.
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