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How climate change and deforestation interact in the transformation of the Amazon rainforest.
Nat Commun
September 2025
Institute of Physics, University of São Paulo, São Paulo, Brazil.
The Amazon rainforest is one of Earth's most diverse ecosystems, playing a key role in maintaining regional and global climate stability. However, recent changes in land use, vegetation, and the climate have disrupted biosphere-atmosphere interactions, leading to significant alterations in the water, energy, and carbon cycles. These disturbances have far-reaching consequences for the entire Earth system.
View Article and Find Full Text PDFPioneering Comparative Proteomic and Enzymatic Profiling of Amazonian Scorpion Venoms Enables the Isolation of Their First α-Ktx, Metalloprotease, and Phospholipase A.
Toxins (Basel)
August 2025
Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-903, SP, Brazil.
Scorpionism is a growing public health concern in Brazil, with the Amazon region presenting the highest mortality rates but remaining understudied, especially regarding local scorpion venoms composition. This study presents the first comprehensive biochemical characterization of venoms from three Amazonian species- (TmetuV), (TsilvV), and (BamazV)-using an integrated approach combining Multi-Enzymatic Limited Digestion (MELD)-based bottom-up proteomics, high-resolution LC-MS/MS, chromatography, zymography, and enzymatic assays. venom was included as a reference.
View Article and Find Full Text PDFSpatiotemporal Dynamics of Dengue in the State of Pará and the Socio-Environmental Determinants in Eastern Brazilian Amazon.
Infect Dis Rep
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Programa de Pos-Graduação em Ciências Ambientais (PPGCA), Instituto de Geociências, Universidade Federal do Pará, Belém 66075-110, PA, Brazil.
Background: The Amazon biome exhibits complex arboviral transmission dynamics influenced by accelerating deforestation, climate change, and socioeconomic inequities.
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The structure of ant assemblages on Amazonian fluvial islands: the roles of recurrent disturbance and isolation.
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August 2025
Programa de Pós-Graduação Em Zoologia, Instituto de Ciências Biológicas, Universidade Federal Do Amazonas, Av. General Rodrigo Otávio 3000, Manaus, AM, 69077-000, Brazil.
Disturbance and dispersal processes jointly shape assemblage structures across multiple spatial scales. The flood pulse in Amazon rivers is a large-scale natural and seasonal disturbance that affects floodplain forests and fluvial islands. We evaluated how flooding and isolation of fluvial islands act as environmental filters, structuring taxonomic and functional ant assemblages in the Amazon.
View Article and Find Full Text PDFDivergent clinical, inflammatory, and histopathological responses induced by Amazonian Tityus venoms: insights and limitations of current antivenom therapy.
Biochimie
August 2025
Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address:
Scorpion stings are considered a neglected condition and represent a serious health problem in many tropical countries, especially for children and the elderly. In Brazil, the yellow scorpion (Tityus serrulatus) is widely found and responsible for the majority of severe envenoming cases; however, other medically relevant species endemic to the Brazilian Amazon region, such as Tityus silvestris, Tityus metuendus and Tityus obscurus, remain underexplored. In the present study, we characterized the clinical, inflammatory and histopathological responses induced by venoms from these Amazonian species in a murine model (Balb/c mice), using T.
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