Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

A review on the use of bile acids as hosts for molecular recognition and enantioresolution is presented. The optical resolution of different classes of organic derivatives, i.e., lactones, aliphatic alcohols, sulfoxides, epoxides, ketones, cyclic amides, cyclic carbonates, and sulfites, may be obtained by host-guest enantioselective inclusion complexation. The salient aspects of the enclathration process, including X-ray diffraction results, are discussed.

Download full-text PDF

Source
http://dx.doi.org/10.1002/chir.20126DOI Listing

Publication Analysis

Top Keywords

bile acid
4
acid derivatives
4
derivatives enantiodifferentiating
4
enantiodifferentiating host
4
host molecules
4
molecules inclusion
4
inclusion processes
4
processes review
4
review bile
4
bile acids
4

Similar Publications

It is helpful for diagnostic purposes to improve our current knowledge of gut development and serum biochemistry in young piglets. This study investigated serum biochemistry, and gut site-specific patterns of short-chain fatty acids (SCFA) and expression of genes related to barrier function, innate immune response, antioxidative status and sensing of fatty and bile acids in suckling and newly weaned piglets. The experiment consisted of two replicate batches with 10 litters each.

View Article and Find Full Text PDF

Safety assessment of potential probiotic lactic acid bacteria strains SY21 and SY22.

Food Sci Biotechnol

October 2025

Department of Food Science and Biotechnology, Gachon University, Seongnam, 13120 Republic of Korea.

Unlabelled: SY21 and SY22 exhibit anti-inflammatory activity; however, their safety has not been evaluated. The suitability as probiotic strains were evaluated by using phenotypic and genotypic analyses. Indole production, urease activity, mucin degradation, bile salt hydrolase activity, β-hemolysis, and gelatin liquefaction activity were not found.

View Article and Find Full Text PDF

Limosilactobacillus fermentum CRL2085, isolated from feedlot cattle rations, displayed high efficiency as a probiotic when administered to animals. A comprehensive genomic analysis was performed to elucidate the genetic basis underlying its probiotic potential. Fifteen genomic islands and CRISPR-Cas elements were identified in its genome.

View Article and Find Full Text PDF

Pyroptosis is a lytic and pro-inflammatory regulated cell death pathway mediated by pores formed by the oligomerization of gasdermin proteins on cellular membranes. Different pro-inflammatory molecules such as interleukin-18 are released from these pores, promoting inflammation. Pyroptotic cell death has been implicated in many pathological conditions, including cancer and liver diseases.

View Article and Find Full Text PDF

Tauroursodeoxycholic acid modulates neuroinflammation via STING/NF-κB inhibition after traumatic brain injury.

Int Immunopharmacol

September 2025

Department of Medical Science Research Center, Brain Injury and Drug Prevention Research Key Laboratory of Shaanxi Universities, Peihua University, Xi'an, Shaanxi 710125, China; Department of Neurosurgery, Bijie Traditional Chinese Medicine Hospital, Bijie 551700, China; School of Life and Health Sc

The incidence of traumatic brain injury (TBI) has demonstrated a marked escalation recently. Nevertheless, there remains a critical paucity of effective drug interventions targeting persistent neuroinflammation-induced damage following TBI. STING/NF-κB axis-induced pyroptosis emerges as a pivotal mechanism driving persistent neuroinflammation, providing it as a potential target for multi-pathway precision therapeutic in TBI.

View Article and Find Full Text PDF