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http://dx.doi.org/10.1038/nature01479 | DOI Listing |
Patient
September 2025
Patient Services, Anthony Nolan, 2 Heathgate Place, London, NW3 2NU, UK.
Background: There is increasing interest in using patient-reported outcome measures (PROMs) to assess quality of life (QoL) following hematopoietic cell transplant (HCT). However, there is limited consensus on how such data should be collected within HCT services. This survey study investigated health professionals (HCPs) views towards QoL data collection and factors affecting the use of PROMs within HCT centres in the UK.
View Article and Find Full Text PDFMol Pharmacol
August 2025
Institute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Biomedical Research Center Seltersberg, Justus Liebig University of Giessen, Giessen, Germany. Electronic address:
The myristoylated preS1 domain (myr-preS1) of the hepatitis B virus (HBV) large surface protein is essential for binding to the receptor protein, Na/taurocholate co-transporting polypeptide (NTCP), and for the subsequent internalization of the virus-receptor complex. NTCP, which is expressed in hepatocytes, plays a physiological role in hepatic bile acid transport. Recent cryo-electron microscopy structures of the myr-preS1-NTCP complex were used to analyze virus-receptor interactions at the molecular level.
View Article and Find Full Text PDFSemin Vasc Surg
September 2025
University of Wisconsin, 600 Highland Ave Madison, WI 53792.
Vascular surgeons are often responsible for navigating treatment decisions when caring for older adults. Care for these patients is informed by the surgeon's assessment of the patient's decision-making capacity, use of advance care planning, and understanding of futility. Having difficult conversations with patients and their families is supported by strategies that promote empathic communication and shared decision making with older adults with serious illness due to, and associated with, vascular disease.
View Article and Find Full Text PDFPsychother Psychosom Med Psychol
September 2025
Abteilung für Medizinische Psychologie und Medizinische Soziologie, Universitätsklinikum Leipzig.
Since 2020, cancer counselling centers (CCCs) have been eligible for funding from health insurance funds under the legal regulation on "Outpatient Cancer Counseling" (§65e SGB V). This article investigates the rationale for or against applying for funding and evaluates the funding option from the perspective of staff members at both funded and non-funded CCCs, as well as sponsoring organizations. The aim is to analyse the practical feasibility of the financing model.
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