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http://dx.doi.org/10.1046/j.1360-0443.2002.00172.x | DOI Listing |
JACC Clin Electrophysiol
March 2025
Department of Cardiology, AZ Sin Jan Bruges, Bruges, Belgium. Electronic address:
Background: Sudden cardiac death (SCD) is generally associated with life-threatening ventricular arrhythmias. Supraventricular arrhythmias are an accepted cause of SCD in Wolff-Parkinson-White syndrome and complex congenital heart disease. However, the role of atrial tachyarrhythmias (ATAs) in SCD in patients with structurally normal hearts is unclear.
View Article and Find Full Text PDFCirculation
July 2023
Icahn School of Medicine at Mount Sinai, New York, NY (M.K.T., V.Y.R.).
Background: Pulsed field ablation is a novel nonthermal cardiac ablation modality using ultra-rapid electrical pulses to cause cell death by a mechanism of irreversible electroporation. Unlike the traditional ablation energy sources, pulsed field ablation has demonstrated significant preferentiality to myocardial tissue ablation, and thus avoids certain thermally mediated complications. However, its safety and effectiveness remain unknown in usual clinical care.
View Article and Find Full Text PDFHepatol Commun
June 2023
University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, Colorado, USA.
Background: Alterations in both mitochondrial DNA (mtDNA) and nuclear DNA genes affect mitochondria function, causing a range of liver-based conditions termed mitochondrial hepatopathies (MH), which are subcategorized as mtDNA depletion, RNA translation, mtDNA deletion, and enzymatic disorders. We aim to enhance the understanding of pathogenesis and natural history of MH.
Methods: We analyzed data from patients with MH phenotypes to identify genetic causes, characterize the spectrum of clinical presentation, and determine outcomes.
Front Vet Sci
June 2022
Dipartimento di Medicina Veterinaria e Scienze Animali (DIVAS), Università degli Studi di Milano, Milan, Italy.
Vitrification and ultra-rapid freezing, which are more commonly used for oocytes and embryos, have recently been applied to spermatozoa in an attempt to make semen cryopreservation in field conditions easier compared to conventional freezing. It is well-known that in case of unexpected death of rare and wild animals, preserving epididymal spermatozoa from isolated testicles represents a great chance of salvaging male germplasm for future use in assisted reproductive technologies. The aim of this study was to evaluate the morphofunctional integrity of cat epididymal spermatozoa ultra-rapid frozen in pellets or straws with two different extenders [E1 (Tris buffer with 20% egg yolk and 0.
View Article and Find Full Text PDFNeurosurg Clin N Am
April 2022
Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Blvd, Phoenix, AZ 85054, USA; Precision Neuro-therapeutics Innovation Lab, Mayo Clinic, Phoenix, AZ, USA; Neurosurgery Simulation and Innovation Lab, Mayo Clinic, Phoenix, AZ, USA; Department of Radiology, Mayo Clinic, 5777 East Mayo Bl
Acute ischemic stroke continues to be a major cause of death and disability globally. Although the concept of endovascular treatment of ischemic stroke is relatively new, current evidence from high-quality randomized trials suggests a significant improvement in the clinical outcome with mechanical thrombectomy up to 24 hours from the stroke onset. There has been a paradigm shift from medical management to mechanical thrombectomy which is now considered standard of care in eligible patients.
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