Nuclear PHGDH regulates macrophage polarization through transcriptional repression of and in breast cancer.

Objective: Tumor-associated macrophages (TAMs) exhibit heterogeneous properties including anti-tumorigenic and pro-tumorigenic phenotypes. The rate-limiting enzyme in serine biosynthesis, 3-phosphoglycerate dehydrogenase (PHGDH), has a well-established role in cellular metabolism, yet its specific role in macrophages remains unknown.

Methods: Metabolomics assays were conducted to assess metabolite composition and dynamics in macrophages.

Timing and Frequency Synchronization Using CAZAC Sequences for OFDM Systems.

Since orthogonal frequency division multiplexing (OFDM) systems are very susceptible to symbol timing offset (STO) and carrier frequency offset (CFO), which cause inter-symbol interference (ISI) and inter-carrier interference (ICI), accurate STO and CFO estimations are very important. In this study, first, a new preamble structure based on the Zadoff-Chu (ZC) sequences was designed. On this basis, we proposed a new timing synchronization algorithm, called the continuous correlation peak detection (CCPD) algorithm, and its improved algorithm: the accumulated correlation peak detection (ACPD) algorithm.

A New Construction of 4q-QAM Golay Complementary Sequences.

Quadrature amplitude modulation (QAM) constellation and Golay complementary sequences (GCSs) are usually applied in orthogonal frequency division multiplexing (OFDM) systems to obtain a higher data rate and a lower peak-to-mean envelope power ratio (PMEPR). In this paper, after a sufficient search of the literature, it was found that increasing the family size is an effective way to improve the data rate, and the family size is mainly determined by the number of offsets in the general structure of QAM GCSs. Under the guidance of this idea, we propose a new construction for 4q-QAM GCSs through generalized Boolean functions (GBFs) based on a new description of a 4q-QAM constellation, which aims to enlarge the family size of GCSs and obtain a low PMEPR.

[Susceptibility and related physiological and biochemical mechanisms of Carposina niponensis Walsingham larvae on six insecticides before and after overwintering].

The study with impregnating method showed that after overwintering, the susceptibility of Carposina niponensis larvae on triazophos, phoxim, chlorpyrifos, malathion, lambda-cyhalothrin and abamectin was 34.50, 16.71, 3.