tRNA-Derived Small RNA Accelerates Tumorigenesis through Crosstalk with Tumor-Associated Macrophages, and Downregulation with Cell Membrane-Modified Polymer Nanoparticles Enables Treatment Response.

Accumulating evidence has shown that tRNA-derived small RNAs (tsRNAs) play pivotal roles in the progression of the majority of malignancies. The tumor microenvironment (TME) is important for hepatocellular carcinoma (HCC) progression. However, how tsRNAs exert their effects through the TME to drive hepatocarcinogenesis is unclear.

ChatGPT in Oncology Diagnosis and Treatment: Applications, Legal and Ethical Challenges.

Purpose Of Review: This study aims to systematically review the trajectory of artificial intelligence (AI) development in the medical field, with a particular emphasis on ChatGPT, a cutting-edge tool that is transforming oncology's diagnosis and treatment practices.

Recent Findings: Recent advancements have demonstrated that ChatGPT can be effectively utilized in various areas, including collecting medical histories, conducting radiological & pathological diagnoses, generating electronic medical record (EMR), providing nutritional support, participating in Multidisciplinary Team (MDT) and formulating personalized, multidisciplinary treatment plans. However, some significant challenges related to data privacy and legal issues that need to be addressed for the safe and effective integration of ChatGPT into clinical practice.