Publications by authors named "Yuri Takehara"
Purpose: is the frequently detected cancer-predisposing gene in female breast cancer. In addition, the association with the risks of other cancer types has been suggested, and clinical management has also been discussed. Although clinical relevance of germline variants differs across population, there is little evidence of the clinical relevance of germline variants in East Asia.
View Article and Find Full Text PDFBackground: Patients with early recurrence of hormone receptor (HR)-positive, HER2-negative (HR+/HER2-) breast cancer have a poor prognosis. We aimed to identify clinical and pathological risk factors for recurrence within three years after surgery of HR+/HER2- breast cancer.
Methods: We retrospectively reviewed clinical data of patients with stage II-III HR+/HER2- breast cancer who received adjuvant endocrine therapy from January 1, 2012 to January 1, 2017 at five institutions.
Article Synopsis
- The study assessed hospital staff's awareness and understanding of breast awareness (BA), which focuses on early detection, and compared it with traditional breast self-examination (BSE).
- An anonymous survey at St. Luke's International Hospital in Japan showed that 78% of participants were previously unfamiliar with BA, but a large majority (89.1%) expressed interest in early detection practices.
- After exposure to an informational leaflet, 98.4% understood BA concepts, and 93.2% were able to differentiate it from BSE, highlighting the leaflet's effectiveness and the need for increased BA awareness among medical professionals.
Background: Radiation-induced angiosarcoma (RIAS) of the breast is a very rare and poor prognostic disease. According to previous studies, the efficacy of chemotherapy for RIAS is still controversial. However, no study has assessed the prognosis of RIAS and the prognostic impact of preoperative or postoperative chemotherapy in Japanese patients.
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