Publications by authors named "Yiannis L Katsogridakis"
Performance of a Molecular Test for Group A Streptococcus Pharyngitis.
J Pediatric Infect Dis Soc
February 2023
We performed a prospective study to determine if the pretest probability of a positive loop-mediated isothermal amplification test is greater when there are more signs and symptoms of GAS pharyngitis. Patients were enrolled if a clinician obtained a GAS RADT. The McIsaac score was calculated.
View Article and Find Full Text PDFObjective: We evaluated the diagnostic utility of the presence and number of cerebrospinal fluid (CSF) bands in distinguishing bacterial from aseptic meningitis among children with CSF pleocytosis.
Methods: We identified retrospectively a cohort of children 29 days to 19 years of age with CSF pleocytosis (> or =10 x 10(6) leukocytes per L) who were treated in the emergency departments of 8 pediatric centers between January 2001 and June 2004 and whose CSF was evaluated for the presence of bands. We performed bivariate and multivariate analyses to determine the ability of CSF bands to distinguish bacterial from aseptic meningitis.
Article Synopsis
- The study aimed to assess how administering antibiotics before a lumbar puncture affects cerebrospinal fluid (CSF) profiles in children with bacterial meningitis.
- Researchers analyzed medical records from 245 children with confirmed or probable bacterial meningitis, particularly noting the impact of antibiotics given within 72 hours prior to the procedure.
- The results indicated that patients who received antibiotics had higher CSF glucose levels and lower protein levels, especially those with more than 12 hours of pretreatment, but the duration of antibiotic therapy did not relate significantly to white blood cell counts in the CSF.
Veinlite transillumination in the pediatric emergency department: a therapeutic interventional trial.
Pediatr Emerg Care
February 2008
Objectives: We hypothesized that transillumination would increase peripheral intravenous (IV) insertion success rates in pediatric emergency department patients. Primary outcome was success in first attempt, and secondary outcome was success within 2 attempts.
Methods: We evaluated IV insertion by pediatric emergency department physicians and nurses using the Veinlite (TransLite, Sugar Land, Tex).
Context: Children with cerebrospinal fluid (CSF) pleocytosis are routinely admitted to the hospital and treated with parenteral antibiotics, although few have bacterial meningitis. We previously developed a clinical prediction rule, the Bacterial Meningitis Score, that classifies patients at very low risk of bacterial meningitis if they lack all of the following criteria: positive CSF Gram stain, CSF absolute neutrophil count (ANC) of at least 1000 cells/microL, CSF protein of at least 80 mg/dL, peripheral blood ANC of at least 10,000 cells/microL, and a history of seizure before or at the time of presentation.
Objective: To validate the Bacterial Meningitis Score in the era of widespread pneumococcal conjugate vaccination.