Obstructive Sleep Apnea and Risk of Respiratory Syncytial Viral Infection: A Retrospective Multi-Institution Cohort Study.

This retrospective cohort study evaluated the association between obstructive sleep apnea (OSA) and the risk of respiratory syncytial virus (RSV) infection and its complications using data from the TriNetX US Collaborative Database. Patients diagnosed with OSA (n = 1 061 261) and matched controls (n = 3 479 494) were identified via ICD-10-CM codes. Propensity score matching adjusted for 19 covariates to balance baseline characteristics.

Nontyphoidal salmonellosis is associated with an increased risk of stroke: Insights from multinational real-world data.

Background: Stroke is a significant cause of morbidity and mortality worldwide, contributing substantially to the global burden of disease. In low- and middle-income countries, stroke tends to occur at younger ages, with infection being one of the notable contributing factors. Previous studies have explored the impact of nontyphoidal Salmonella (NTS) on vascular and blood-related diseases, with animal experiments confirming related mechanisms.

Medication use patterns in pregnant women with psoriasis: a nationwide study in Taiwan.

Background: Psoriasis, an autoimmune skin condition, affects 2-4% of the global population, with significant prevalence among women of childbearing age. Pregnancy presents challenges in managing psoriasis because of hormonal changes and treatment safety concerns. Understanding treatment patterns in pregnant women is crucial, given limited real-world evidence.

Egalitarian penalty or reward? A longitudinal study of adolescent gender attitudes and adulthood income.

Studies often attribute the persistent gender pay gap to different labor force experiences between men and women. Yet, attitudes formed in earlier life stages also critically shape individual outcomes. Using longitudinal data from Taiwan, this study examines whether and how adolescents' gender attitudes are related to income in young adulthood.

Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors.

Tumor biomarkers are developed to indicate tumor status, clinical outcome, or prognosis. Since currently there are no effective biomarkers for canine mammary tumor (CMT), this study intended to verify whether kynurenine 3-monooxygenase (KMO), one of the key enzymes involved in tryptophan catabolism, is competent for predicting prognosis in patients with CMT. By investigating a series of 86 CMT clinical cases, we found that both gene and protein expression of KMO discriminated malignant from benign CMTs and was significantly higher in stage IV and V tumors than in lower-stage CMTs.

Do grandparents matter? A multigenerational perspective on educational attainment in Taiwan.

In response to the growing interest in multigenerational effects, we investigate whether grandparents' education affects grandchildren's transitions to academic high school and university in Taiwan. Drawing on social capital literature, we consider potential heterogeneity of the grandparent effect by parents' characteristics and propose that grandparents' education yields differential effects depending on parents' education. Our results show tenuous effects of grandmother's and grandfather's years of schooling, net of parents' education.

It's Not Just About the Money: Gender and Youth Migration from Rural China.

Statistics suggest that young men and women in China migrate at almost equal numbers, but we know less about gender differences in the decision to migrate. We examine the factors associated with the decision to migrate and the rationales given by young migrants. Our results are consistent with previous figures and show no overall gender differences in susceptibility to migration.

Surfection: a new platform for transfected cell arrays.

Efficient high-throughput expression of genes in mammalian cells can facilitate large-scale functional genomic studies. Towards this aim, we developed a simple yet powerful method to deliver genes into cells by cationic polymers on the surface of substrates. Transfection can be achieved by directly contacting nucleic acid-cell mixtures with the cationic substrates, e.