Portable and affordable device for on-site quantitative detection of somatic cells in milk.

Antimicrobial resistance in mastitis-associated pathogens has heightened concerns over the safety of raw milk, which transmits pathogens from animals to humans. Elevated somatic cell count (SCC) is widely recognized as a key indicator of microbial quality in milk, often linked to mastitis infections. High SCC alters milk composition, compromises milk quality, and reduces shelf life, rendering it unsuitable for consumption.

Cytotoxin antibody-based colourimetric sensor for field-level differential detection of elapid among big four snake venom.

Development of a rapid, on-site detection tool for snakebite is highly sought after, owing to its clinically and forensically relevant medicolegal significance. Polyvalent antivenom therapy in the management of such envenomation cases is finite due to its poor venom neutralization capabilities as well as diagnostic ramifications manifested as untoward immunological reactions. For precise molecular diagnosis of elapid venoms of the big four snakes, we have developed a lateral flow kit using a monoclonal antibody (AB1; IgG1 - κ chain; Kd: 31 nM) generated against recombinant cytotoxin-7 (rCTX-7; 7.

Colorimetric aptasensor for on-site detection of oxytetracycline antibiotic in milk.

Oxytetracycline (OTC), one of the largely used antibiotic in veterinary practice has been banned due to its potential side effects. Development of a field applicable and affordable kit to detect OTC will help to eliminate such milk from human consumption. An aptamer has been designed (27 nt; K = 29.